It is important to prevent nausea and vomiting to maintain both the quality of life of patients with cancer and the efficacy of chemotherapy. The aim of this study was to examine the efficacy of aprepitant for treatment of chemotherapy-induced nausea and vomiting (CINV) in Japanese patients with gastrointestinal cancer receiving highly or moderately emetogenic chemotherapy (HEC or MEC) regimens...

A systematic study of the effects of polymer surface properties on the interaction with human endothelial cells (HEC) may lead to the development of small-diameter vascular grafts. HEC, suspended in culture medium containing 20% serum adhered and spread onto moderately wettable polymers such as TCPS (tissue culture polystyrene). Reduced or no adhesion of HEC was observed upon the hydrophobic po...

An image based model reconstruction system is described. Real images of a rigid object acquired under a simple but controlled environment are used to recover the three dimensional geometry and the surface appearance. Proposed system enables robustly modeling of small artifacts with high resolution geometry and surface appearance. Such artifacts may have handles, holes, concavities, cracks, etc....

Hec-6st is a highly specific high endothelial venule (HEV) gene that is crucial for regulating lymphocyte homing to lymph nodes (LN). The enzyme is also expressed in HEV-like vessels in tertiary lymphoid organs that form in chronic inflammation in autoimmunity, graft rejection, and microbial infection. Understanding the molecular nature of Hec-6st regulation is crucial for elucidating its funct...

L-selectin, a Ca(2+)-dependent lectin-like receptor, mediates lymphocyte attachment to high endothelial venules (HEV) of peripheral lymph nodes (PLN) during the process of lymphocyte homing. Two endothelial-derived ligands for L-selectin, known as GlyCAM-1 (Sgp50) and CD34 (Sgp90), have been identified by affinity precipitation of lymph node extracts with a chimeric molecule that combines the e...

BACKGROUND/AIMS Osteopontin (OPN) is an Extracellular Matrix (ECM) molecule and is involved in many physiologic and pathologic processes, including cell adhesion, angiogenesis and tumor metastasis. OPN is a well-known multifunctional factor involved in various aspects of cancer progression, including endometrial cancer. In this study, we examined the significance of OPN in endometrial cancer. ...

It is expected that our HEC system will enter exascale era in decade, which is one thousand times of performance as today’s system (petascale). In the mean time, many challenges also have been noticed and pointed out, as the size of HEC system increased without some dispensable improving on architecture of today’s HEC system, the systems could collapse at exascale, because the functionality wou...

Abstract Various hydrological models were used in different river basins to simulate the runoff on available rainfall, land use and soil property data. The HEC-HMS model is by several researchers estimate water potential of basin through rainfall-runoff modeling. In this study, a for Punpun has been developed using HEC-HMS. Daily rainfall data from years 2005 2017 development model. ArcGIS anal...

Glucose metabolism was studied in ewes fed 800 g chopped alfalfa hay (H) or 400 g alfalfa hay and 400 g corn grain given in whole (HWC), ground (HGC) or extruded (HEC) form. Daily intake of metabolisable energy and crude protein were: 5.8 MJ, 109 g; 9.0 MJ, 84 g; 9.5 MJ, 84 g and 8.5 MJ, 88 g in H, HWC, HGC and HEC, respectively. In situ ruminal degradability ranked whole, ground, and extruded ...

most of river engineering problems are complicated and need to be analyzed by three dimensional models of flow and sediment transport. considering the fact that computers and numerical methods with great ability of flow and sediment transport simulation are developing quickly, using numerical modeling by engineers is inevitable. nevertheless, before application, numerical models need to be veri...