BACKGROUND Depersonalization disorder (DPD) is characterized by a subjective sense of unreality, disembodiment, emotional numbing and reduced psychogenic (sudomotor) sympathoexcitation. AIMS Three related experiments utilized escalating physical and emotional challenges in 14 DPD participants and 16 controls aimed to elucidate (i) whether the cardiovascular sympathetic (SNS) and parasympathet...

Modern communications systems will have to integrate multiple radio technologies to support a large number of wireless standards (WLAN, WPAN...). This system should operate with third generation (3G) air interface standards, where non constant envelope modulation formats (MQAM, OFDM...) are required. The amplification of a modulated signal with large variation of envelope introduces distortions...

In this paper, new digital predistortion (DPD) solutions for power amplifier (PA) linearization are proposed, with particular emphasis on reduced processing complexity in future 5G and beyond wideband radio systems. The first proposed method, referred to as the spline-based Hammerstein (SPH) approach, builds complex spline-interpolated lookup table (LUT) followed by a linear finite impulse resp...

Non-linearity of wireless transceivers, specifically power amplifier (PA) non-linearity, could pose major limitations towards having high throughput, and cost energy efficient communication systems. Such from the PA is typically compensated in transmitter, e.g. by applying back-off or performing digital-pre-distortion (DPD) aiming to linearize transmitter. However, leads lower efficiency, outpu...

In this article, a novel digital predistortion (DPD) solution for fully multiple-input–multiple-output (MIMO) transmitters (TXs) is proposed. Opposed to classical DPD solutions that operate at TX chain or antenna level, the proposed operates stream beam and hence, its complexity proportional number of spatially multiplexed streams users rather than antennas. addition, beam-level in frequency do...

PURPOSE Dihydropyrimidine dehydrogenase (DPD)-deficient cancer patients have been shown to develop severe toxicity after administration of 5-fluorouracil. Routine determination of DPD activity is limited by time-consuming and labor-intensive methods. The purpose of this study was to develop a simple and rapid 2-(13)C-uracil breath test, which could be applied in most clinical settings to detect...

We investigated a therapeutic strategy for recurrent malignant gliomas using mesenchymal stem cells (MSC), expressing cytosine deaminase (CD), and prodrug 5-Fluorocytosine (5-FC) as a more specific and less toxic option. MSCs are emerging as a novel cell therapeutic agent with a cancer-targeting property, and CD is considered a promising enzyme in cancer gene therapy which can convert non-toxic...

Distributed optimization is ubiquitous in emerging applications, such as robust sensor network control, smart grid management, machine learning, resource slicing, and localization. However, the extensive data exchange among local central nodes may cause a severe communication bottleneck. To overcome this challenge, over-the-air computing (AirComp) promising medium access technology, which explo...