OBJECTIVE The aim of this study was to assess the 12-week efficacy of desvenlafaxine in treating moderate to severe vasomotor symptoms and the clinical relevance of improvements in postmenopausal women experiencing 50 or more moderate to severe hot flashes per week. METHODS Participants were randomized to placebo or desvenlafaxine 100 mg/day in the 12-week efficacy substudy of a year-long, mu...

Methods Children admitted for evaluation of gastrointestinal symptoms after fish ingestion. Skin Prick Tets (SPT) with commercial extracts of codfish, hake, sole, tuna, herring, haddock were performed. Specific IgE to fish was also determined. Patch test with the same extracts for SPT were applied 48h and read at 2 and 24 hours after removing. Open Oral challenge (OOC) was performed when diagno...

Raw fish consumption is increasing worldwide. Since around the year 2000, western regions of Japan have reported a foodborne disease of unknown cause that occurred after the consumption of flounder. In October 2010, a particularly large outbreak was reported in these regions among individuals who consumed flounder fish that had been raised in aquaculture systems. The median incubation period wa...

OBJECTIVE To conduct a pilot study evaluating a procedure for assessment of daily symptoms and functioning in pediatric patients. METHOD Participants included 11 parent-child dyads referred to a tertiary care center for evaluation of constipation and abdominal pain. Each family was provided a hand-held computer and modem. For 7 consecutive days, parents and children (ages 6-10 years) responde...

In January 2008, an outbreak of acute gastroenteritis at a waterpark was reported to the Bundang-gu Public Health Center in Seongnam, Korea. To determine the etiological agent and mode of transmission, a retrospective cohort study was done using structured questionnaires and stool samples from patients who had current gastrointestinal symptoms and three food handlers were tested. A total of 67 ...

OBJECTIVES This study examined potential benefits of diagnosing and treating elderly adults with overactive bladder (OAB) symptoms. METHODS Data were analysed from the OAB Re-Contact Study (N = 2750), a cross-sectional, self-reported Internet survey. Elderly respondents (65+ years old) with OAB were identified according to current medication use to control OAB symptoms or by scores > 14 (men)...

Over a 2-month period, 43 of 143 participating general practitioners included 97 patients with 113 health impairments, mainly gastrointestinal problems (35%), respiratory tract infections (30%), and skin diseases (11%). Systemic febrile illness or imported tropical disease accounted for less than 4% of cases.

To understand the transmission of Cryptosporidium infection in children, fecal specimens from 62 Kuwaiti children with gastrointestinal symptoms found to be positive by microscopy were genotyped and subtyped with a small subunit rRNA-based PCR-restriction fragment length polymorphism analysis and a 60-kDa glycoprotein-based DNA sequencing tool. The median age of infected children was 4.5 years,...

Antidepressant drugs are widely used in the treatment of many psychiatric disorders. The decision to discontinue medication after a successful course of treatment, as well as accidental or planned interruptions to treatment, may, in susceptible patients, result in troublesome symptoms which are generally termed "discontinuation". Discontinuation symptoms are now known to be associated with most...

OBJECTIVE To estimate the prevalence of dyspepsia in the general population aged over 20 in western Iran. METHODS The cross-sectional study was conducted among the randomly selected general population over the age of 20 years in Sanandaj city. Iran, from April to December 2009. A questionnaire containing demographic, symptoms and history variables was used. Dependent variables were self-repor...