Pancreatic acinar cells synthesise and secrete a variety of digestive enzymes as well as a NaCI-rich pancreatic juice. Acinar cells are able to adapt to the changing needs of the organism both by regulating the total pancreatic mass as well as by altering the synthesis of specific molecules. Adaptive regulation occurs with the onset of oral feeding at birth, the regrowth that follows surgical r...

To test the potential of diet switching experiments in ecophysiological studies of marine invertebrate, stable carbon isotope ratios were measured at different seasons in the gonad, adductor muscle, digestive gland and gills of scallops (Pecten maximus) and oysters (Crassostrea gigas) held for 15 days on a constant diet of phytoplankton depleted in 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 4...

Metallothionein (MT) is a sulfhydryl-rich protein involved mainly in heavy metal homeostasis and detoxification. In this study, the use of the mussel as an experimental model allowed us to test MT antioxidant properties at the molecular, cellular, and organism level. MT induction was achieved by mussel exposure to Cd (200 μg/l) in aquaria for 7 days followed by detoxification in the sea for 28 ...

The aim of the present study was to measure the early effects of copper (10 and 50 μg L(-1)), cadmium (2, 10, and 50 μg L(-1)) and mixtures of these metals in the freshwater bivalve Corbicula fluminea exposed for 12 h in laboratory. Transcription levels of superoxide dismutase (SOD), catalase (CAT), selenium-dependent glutathione peroxidase (Se-GPx), pi-class glutathione S-transferase (pi-GST),...

We compared lipid dynamics and the physiological responses of blue mussels Mytilus edulis, a cold-adapted species, and oysters Crassostrea virginica, a warmer-water species, during simulated overwintering and passage to spring conditions. To simulate overwintering, animals were held at 0 degrees C, 4 degrees C and 9 degrees C for 3 months and then gradually brought to and maintained at 20 degre...

In the marine environment, sessile cyanobacteria have developed chemical strategies for protection against grazers. turn, herbivores to circumvent these defenses and in certain cases even take advantage of them as shelter from their own predators. This is case Stylocheilus striatus, a sea hare that feeds on Anabaena torulosa, cyanobacterium produces toxic cyclic lipopeptides laxaphycin B family...

Metastasis to the head and neck and more specifically to the thyroid gland from distant primary tumors is less common in comparison to the local regional metastasis of squamous cell carcinomas of the upper aero-digestive tract. Preoperative diagnosis of these cases can be difficult. The authors present three cases with distant solitary metastases of clear renal cell carcinoma to the thyroid gla...

The objective was to observe the influence of hypophysectomy on the secretory cells of digestive glands in the mouse and to compare these findings with those reported for other mammalian species. Hypophysectomy of the mouse induced involutional changes in glandular cells concerned with secretion of proteins and mucins, and in those involved in ion transport or release. Gastric chief cells, panc...

Breast milk is a complex biological fluid. Additionally to its nutritional impact, it contains diverse bioactive elements related early metabolic programming and molecular structures, such as microRNA the epigenetic signaling process. Now, we know that human not sterile significant diversity of microorganisms bacteria (bacterioma), viruses (viroma) fungi (mycobiome), all which integrate concept...