Cardiovascular MR (CMR) has an emerging role in the noninvasive diagnostic assessment of heart failure (HF). Different imaging sequences allow for a detailed assessment of cardiac morphology, function, myocardial perfusion, tissue characterization, and blood flow measurement. This article reviews the key applications of CMR in HF, with special focus on how CMR may influence the diagnostic and t...

MOTIVATION Finding diagnostic patterns for fighting diseases like Burkholderia pseudomallei using biomarkers involves two key issues. First, exhausting all subsets of testable biomarkers (antigens in this context) to find a best one is computationally infeasible. Therefore, a proper optimization approach like evolutionary computation should be investigated. Second, a properly selected function ...

Gastric cancer (GC) is one of the leading causes of cancer mortality, worldwide. Molecular understanding of GC’s different subtypes is still dismal and it is necessary to develop new subtype-specific diagnostic and therapeutic approaches. Therefore developing comprehensive research in this area is demanding to have a deeper insight into molecular processes, underlying these subtypes. In this st...

This paper intends to an integrated view of the advances in automated diagnostic systems. The paper includes illustrative and detailed information about automated diagnostic systems and feature extraction/selection from biomedical signals. In this respect, the paper satisfies the automated diagnostic systems, which includes the spectral analysis techniques, feature extraction and/or selection m...

A key criticism of the main diagnostic tool in psychiatry, the Diagnostic and Statistical Manual of Mental Health Disorders (DSM-IV), is that it lacks a biological footing. In this article, we argue for a biological approach to psychiatry based on 'neurocognitive endophenotypes', whereby changes in behavioural or cognitive processes are associated with discrete deficits in defined neural system...

OBJECTIVE This paper describes recent advances in the neurobiology of mental retardation, emphasizing new diagnostic resources provided by cytogenetics, molecular testing, and neuroimaging. SOURCES OF DATA MEDLINE (January 2000 through October 2003), using the following key words: mental retardation, developmental disability, child, and adolescent. Search of the Pediatrics and New England Jou...

realizing the cause of cushing's syndrome (cs) is one of the most challenging processes in clinical endocrinology. the long high dose dexamethasone suppression test (standard test) is costly and need an extended inpatient stay. in this study we want to show the clinical utility of the overnight 8 mg dexamethasone suppression test (dst) for differential diagnosis of cs in a referral center. retr...

introduction :  despite  recent  advances  in  treatment  of  oral  cancer,  it  still causes high rates of mortality and morbidity worldwide. delays in diagnosis and treatment of these cancers greatly affect the prognosis.  this study aimed to assess the treatment delay and its relation to diagnostic delay among oral cancer patients in tehran, iran. materials and methods : we studied 100 patie...

background: cd52 is a small glycoprotein with a gpi anchor at its c-terminus. cd52 is expressed by normal and malignant t and b lymphocytes and monocytes. there are detectable amounts of soluble cd52 in plasma of patients with cll and could be used as a tumor marker. although the biological function of cd52 is unknown but it seems that cd52 may be involved in migration and activation of t-cells...