نتایج جستجو برای: diacetylmonoxime
تعداد نتایج: 167 فیلتر نتایج به سال:
Reactive methylene group at C2 position in dimedone plays an important role in the synthesis of a variety of organic ligands. Condensed compounds 3, 5, 7 were synthesized by reaction with dimedone and different aromatic aldehydes. Synthesized condensed compounds 3, 5 and 7 were on reaction with hydroxyl amine hydrochloride to yield oximes ligands 8, 9 and 10 respectively. The synthesized oxime ...
As new applications for many organophosphate (OP) compounds are discovered, the use of OP compounds has gained importance and this trend is like to continue in the years ahead. In many developing countries, particularly in India, pesticides are being indiscriminately used at every stage to kill a variety of pests that cause harm to agricultural crops. Unfortunately these pesticides are causing ...
Ca sensitizers may be advantageous for treatment in human heart failure by increasing cardiac force without increasing the Ca transient or energy consumption. To study the mode of action of the Ca sensitizers EMD 57033 (EMD) and CGP 48506 (CGP), their influence on butanedione monoxime (BDM)mediated depression of cross-bridge cycling was analyzed in human myocardium (explanted hearts, dilated ca...
Lespedeza cuneata is an introduced legume that is invasive in the tallgrass prairie system and open woodlands of North America. This system includes native Lespedeza species that coexist with L. cuneata, including L. capitata and L. virginica. Previous research has indicated that L. cuneata exudates have profound influences on soil biological functions. The goal of this current research was to ...
Effect Unveils Inter-head Cooperativity and Strain-dependent ADP Release in Fast Skeletal Actomyosin
Amrinone is a bipyridine compound with characteristic effects on the force-velocity relationship of fast skeletal muscle, including a reduction in the maximum shortening velocity and increased maximum isometric force. Here we performed experiments to elucidate the molecular mechanisms for these effects, with the additional aim to gain insight into the molecular mechanisms underlying the force-v...
Doxorubicin (DOX) is a well-established chemotherapeutic drug widely used to treat a variety of cancers, though its clinical use is restricted by irreversible cardiotoxicity. Earlier studies show beetroot juice (BRJ) as a potent chemopreventive agent; however its cardioprotective function is yet to be established. The purpose of this experiment is to determine the protective effect of BRJ again...
The opioid receptor-like 1 (NOP or ORL1) receptor is a G protein-coupled receptor whose endogenous ligand is the heptadecapeptide, nociceptin (Noc). NOP receptors are known to modulate pain processing at spinal, supraspinal and peripheral levels. Previous work has demonstrated that NOP receptors inhibit N-type Ca channel currents in rat sympathetic stellate ganglion (SG) neurons via pertussis t...
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