نتایج جستجو برای: diabetes prevention

تعداد نتایج: 506662  

Journal: :Pediatric clinics of North America 2009
Diane K Wherrett Denis Daneman

Prevention of loss of b cells in type 1 diabetes is a major goal of current research. Knowledge of the genetic susceptibility, increasing ability to predict who may be at risk, recognition of the potential clinical impact of residual insulin secretion after diagnosis, and development of new immunomodulatory agents have supported an increasing number of clinical trials to prevent b-cell loss. In...

Journal: :British medical bulletin 2011
S L Thrower P J Bingley

INTRODUCTION/BACKGROUND Type 1 diabetes is a chronic autoimmune condition characterized by destruction of insulin-producing β cells within the pancreatic islets. It is associated with considerable morbidity and mortality. Incidence levels are rising worldwide. SOURCES OF DATA Pubmed search (Nov 2010) using keywords: Type 1 diabetes, prevention, trials, immunotherapy. AREAS OF AGREEMENT The ...

2013
Emilio Giugliano Elisa Cagnazzo Brunella Giugliano Donatella Caserta Massimo Moscarini Roberto Marci

Physical activity and dietary advice represent the first choice and they are the most studied as well. They represent a non-pharmacological option and have a positive impact on insulin resistance although they do not seem to prevent the gestational diabetes onset.The preconceptional use of metformin in women with polycystic ovary syndrome protects the pancreatic beta cell reserve preventing or ...

2017
Jonathan E. Shaw Richard W. Simpson

The numbers of people with type 2 diabetes are rising rapidly around the world, making it imperative to develop and introduce methods of preventing the condition. A series of clinical trials over the last decade has shown conclusively that lifestyle interventions focusing on physical activity, diet, and weight loss can reduce the risk of developing type 2 diabetes by approximately 60%. Trials e...

Journal: :Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 2010
J Lindström A Neumann K E Sheppard A Gilis-Januszewska C J Greaves U Handke P Pajunen S Puhl A Pölönen A Rissanen M Roden T Stemper V Telle-Hjellset J Tuomilehto D Velickiene P E Schwarz T Acosta M Adler A AlKerwi N Barengo R Barengo J M Boavida K Charlesworth V Christov B Claussen X Cos E Cosson S Deceukelier V Dimitrijevic-Sreckovic P Djordjevic P Evans A-M Felton M Fischer R Gabriel-Sanchez M Goldfracht J L Gomez M Hall H Hauner J Herbst N Hermanns L Herrebrugh C Huber U Hühmer J Huttunen A Jotic Z Kamenov S Karadeniz N Katsilambros M Khalangot K Kissimova-Skarbek D Köhler V Kopp P Kronsbein B Kulzer D Kyne-Grzebalski K Lalic N Lalic R Landgraf Y H Lee-Barkey S Liatis J Lindström K Makrilakis C McIntosh M McKee A C Mesquita D Misina F Muylle A C Paiva B Paulweber M Peltonen L Perrenoud A Pfeiffer F Raposo T Reinehr C Robinson U Rothe T Saaristo J Scholl S Spiers B Stratmann J Szendroedi Z Szybinski T Tankova G Terry D Tolks F Toti A Undeutsch C Valadas P Valensi P Vermunt R Weiss J Wens T Yilmaz

When we ask people what they value most, health is usually top of the list. While effective care is available for many chronic diseases, the fact remains that for the patient, the tax payer and the whole of society: prevention is better than cure. Diabetes and its complications are a serious threat to the survival and well-being of an increasing number of people. It is predicted that one in ten...

2014
Richard W. Seidel Kimberlee A. Pardo Paul A. Estabrooks Sarah S. Wall Brenda M. Davy Fabio A. Almeida

OBJECTIVE The purpose of this study was to identify patient preferences for different components of a local diabetes prevention program that would improve reach. A secondary purpose was to determine if patient characteristics were related to program preferences. METHODS Participants were identified through electronic medical records from two family medicine clinics in Virginia. Participants c...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2012
Ronald B Goldberg Kieren Mather

This review describes the effect of lifestyle change or metformin compared with standard care on incident type 2 diabetes and cardiometabolic risk factors in the Diabetes Prevention Program and its Outcome Study. The Diabetes Prevention Program was a randomized controlled clinical trial of intensive lifestyle and metformin treatments versus standard care in 3234 subjects at high risk for type 2...

Journal: :Preventing Chronic Disease 2005
Christopher A Taylor Kathryn S Keim Dale R Fuqua Christine A Johnson

INTRODUCTION American Indians have a disproportionately higher risk of developing type 2 diabetes. Few data are available about the perceptions of diabetes among American Indians, and no culturally appropriate tools are available for assessment of perceptions related to health and diabetes. METHODS A diabetes prevention assessment tool was developed to measure perceptions of health and diabet...

Journal: :Diabetes care 2003
Zachary T Bloomgarden

The changing shape of childhood Francine Kaufman gave the outgoing President’s Address, discussing our burgeoning societal recognition of obesity as a health problem for children. She traced the differing environments of the child of 40,000 years ago through that experienced today. For the neolithic child, levels of physical activity were high. Approximately one-third of energy intake came from...

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