Mohr-Tranebjaerg syndrome (MTS/DFN-1) or deafness/dystonia syndrome results from a mutation in deafness/dystonia protein 1/translocase of mitochondrial inner membrane 8a (DDP1/TIMM8a). DDP1/TIMM8a is similar to a family of yeast proteins in the mitochondrial intermembrane space which mediate the import and insertion of inner membrane proteins. We now show that TIMM8a assembles in a 70 kDa compl...

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A total of 24 patients with a mean age of 45.8 +/- 20.8 were included in the study. The patients were grouped as Control (C), Degenerative Syndromes (DS), Degeneration Associated with External Factors (DEF), Degeneration Associated with Focal Neurologic Lesion (DFN) and Demyelinating Disease (DM). Imaging started 15 minutes for early and 4 hours for delayed scans after i.v. infusion of I-123 IM...

Introduction: Clinical and pathological heterogeneity in aggressive B-cell non-Hodgkin lymphomas may be driven by several mechanisms of oncogenesis, such as translocations involving the immunoglobulin locus proto-oncogenes, ‘cell-of-origin’ from germinal center (GC), viral associations. Previous classifications have been defined one or more these characteristics transforming events. However, tr...

Oil and gas exploration professionals have begun to focus more on unconventional oil reserves in recent years as a result of their increased efforts. Fractures significant impact the permeability connectivity reservoirs crucial component rock mechanics hydraulics, which directly affects production gas. The identification fracture development zones or micro faults, well how adequately define fra...

DandeLiion (available at dandeliion.com) is a robust and extremely fast solver for the Doyle Fuller Newman (DFN) model, standard electrochemical model (dis)charge of planar lithium-ion cell. conserves lithium, uses second order spatial discretisation method (enabling accurate computations using relatively coarse discretisations) many times faster than its competitors. The code can be used "in c...

Abstract A discrete fracture network (DFN) model based on non-parametric kernel density estimators (KDE) and directional-linear statistics is developed. The provides a characterization of the with distributions orientation size jointly. solution to Bertrand paradox used for calculation disk sizes from trace lengths, latter calculated intersection disks highwall faces by triangulation. Poisson p...

As digitization is increasing, threats to our data are also increasing at a faster pace. Generating fake videos does not require any particular type of knowledge, hardware, memory, or computational device; however, its detection challenging. Several methods in the past have solved issue, but computation costs still high and highly efficient model has yet be developed. Therefore, we proposed new...

In pressure sensitive reservoirs, interaction effects among the porous media flow field, the fracture field and the stress field can cause some specific flow characteristics entirely different from those in conventional reservoirs. Dynamic fracture behavior is one of them, which generates a change in the value of fracture aperture and even a variation in the anisotropy of permeability. In this ...

We have used three highly polymorphic microsatellite repeats from Xq21 to type families in whom a gene for X linked deafness with perilymphatic gusher (DFN 3) was segregating. All three markers were tightly linked to the disease in its radiologically normal and abnormal forms, with a maximum lod score of 10.37 with DXS995 and 8.44 with DXS986 at zero recombination, and 14.03 with DXS1002 at the...