Background The X-linked cyclin-dependent kinase like 5 (CDKL5/STK9) gene has been shown to be responsible for a severe encephalopathy condition characterized by early onset of epilepsy and severe developmental delay. CDKL5 mutations have been shown to be more frequent among female patients. Results Here we report a 6- month male patient, second child of a healthy non consanguineous in the Irani...

BACKGROUND Although children with developmental delay are known to have increased health care use, it is unclear what proportion of that health care use is related to associated chronic health conditions. OBJECTIVES To assess the prevalence of isolated developmental delay and to determine the role of developmental delay in health care use controlling for chronic health conditions. DESIGN Re...

 Background & Objective:  Low birth weight is considered as one the causes of infant mortality across the world. Accordingly, paying attention to neonatal growth leads to mortality rate decrement and consequently prevents future physical and mental disabilities in this age group.  Materials & Methods:  This historic (retrospective) cohort study was conducted on 280 one-year-old male and female...

OBJECTIVE To report the clinical profile of children with mental retardation and developmental delay diagnosed by the Child Assessment Service. DESIGN Retrospective study. SETTING Child Assessment Service, Department of Health, Hong Kong. PARTICIPANTS Data pertaining to the children with mental retardation and developmental delay were drawn from an in-house clinical information system in ...

OBJECTIVES To estimate the prevalence of developmental delay and service use among children in the child welfare system and to identify factors that influence these outcomes. DESIGN A descriptive study using wave 1 of the National Survey of Child and Adolescent Well-Being. PARTICIPANTS AND SETTING Children aged 0 to 10 years (n = 4324) and their caregivers were interviewed within 60 days of...

objective assessment of risk predictors for adverse neurodevelopmental outcome at 1 year of age in term and near-term infants. material & methods this case-control study was a representative sample of infants from different health-care centers of north and east of tehran. the association between risk factors and delayed motor development (developmental quotient below 70 indicating a significant...

Background: Prematurity is the most common cause of death and disability And Preterm infants, are prone to developmental complications. For this reason this study was designed for follow up of these babies until 2 years by modified DDST-2. Methods: This study was a prospective longitudinal descriptive study from March 2009 to March 2011 in clinic of sheikh and Imam Reza Hospitals, mashhad, Iran...