Coenzyme Q(10) (CoQ(10)) is an essential electron carrier in the mitochondrial respiratory chain and an important antioxidant. Deficiency of CoQ(10) is a clinically and molecularly heterogeneous syndrome, which, to date, has been found to be autosomal recessive in inheritance and generally responsive to CoQ(10) supplementation. CoQ(10) deficiency has been associated with five major clinical phe...

Lipids are an essential part of the human diet affecting biological processes and reducing disease development. Plant-based oils, specifically sterols, compounds for cellular composition proliferation. As vegetarians refrain from consuming animal products, although many versions this lifestyle exist, plant oils their only source fat intake. Extracted fats fatty acids; hence study aims to addres...

PURPOSE OF REVIEW To examine current evidence for dietary supplementation with zinc and other micronutrients for primary prevention of multiple micronutrient deficiencies that are known to result from therapies used in the treatment of gastrointestinal inflammatory disorders. RECENT FINDINGS Epidemiological observations and clinical findings have strengthened the concept that both nutritional...

The cognitive deficiencies are the spectrum of deficiencies related to the reduction of brain cognitive capability. They mainly affect decision-making, reasoning, planning and solving capabilities of daily activities. The consequence is cognitively impaired people become dependent by families, caregivers or Health Institutes. Not-intrusive information technology applications can be applied onto...

A Design Pattern presents a proven solution to a common design problem using a combination of informal text, diagrams, and examples. Often, to suitably describe an issue, the author of a Design Pattern must spread and repeat information throughout the Pattern description. Unfortunately, spreading the information can make it difficult for a reader to grasp subtleties in the design, leading to po...

In this paper we present that the logical models in UML can be made better in three ways. Firstly these can avoid the limited ways of using UML to overcome two deficiencies: i. the ambiguous interpretation of classes, and ii. a lack of one to one correspondence with the textual representations of the models. Secondly the models can be hierarchical based on the notions of entity, collection, rel...

BACKGROUND Living with a chronic disease, such as primary antibody deficiency, will often have consequences for quality of life. Previous quality-of-life studies in primary antibody deficiency patients have been limited to different treatment methods. We wanted to study how adults with primary antibody deficiencies manage their conditions and to identify factors that are conducive to coping, go...

OBJECTIVE To examine the prevalence and risk factors of vitamin deficiencies among older Thai adults. METHODS The cross-sectional study was conducted in four rural communities, one from each of the four main regions of Thailand. In total, 2336 subjects aged 60 years and over were recruited. Anthropometric variables, demographic data, blood glucose and lipid profile, albumin, globulin and bloo...

Mitochondrial dysfunction is commonly observed in degenerative disorders, including Alzheimer's and Parkinson's disease that are characterized by the progressive and selective loss of neuronal subpopulations. It is currently unclear, however, whether mitochondrial dysfunction is primary or secondary to other pathogenic processes that eventually lead to age-related neurodegeneration. Here we est...

Eighty-eight percent of countries face the serious burden malnutrition either two or three forms, such as acute and/or chronic undernutrition, micronutrient deficiencies, obesity, and diet-related diseases (including type II diabetes, cardiovascular diseases, certain types cancer) [...]