The integument consists of the skin, and a variety of skin derivatives. In humans, these include hair, nails and several types of glands. In other mammals, these cutaneous appendages include scales, quills, spines, claws, hooves, and horns. The skin consists of a superficial epithelial component, the epidermis, and an underlying layer of connective tissue, the dermis. Together these layers cove...

A 23-year-old woman presented with an 8-year history of progressive diffuse plane xanthomata of the face and neck. Beginning at the earlobes and neck, these yellowish maculopapular lesions had spread over the whole face and neck region, making the patient look as if she were wearing a mask (Figure 1A and Figure 2A). Histologic features were typical for plane xanthoma with multiple foam cells su...

Eccrine angiomatous hamartomas are benign vascular and eccrine malformations often accompanied by hyperhidrosis or pain, increased eccrine glands, and aggregates of vessels. Verrucous hemangiomas are congenital vascular malformations presenting as unilateral grouped papules. Histologically, they show verrucous epidermal change and proliferation of capillaries in the dermis. We report a case of ...

A 57-year-old Japanese man presented with a 10-year history of a plaque on his face. The lesion had gradually increased in volume. Physical examination revealed a brownish-grey plaque, approximately 5 x 5 cm in size, with ulcération on the right nasolabial area (Fig. la). Dermoscopy showed a milky-red area with some milia-like cysts and dilated vessels on the surface (not shown). Histopathologi...

Soft tissue augmentation is a process of implanting tissues or materials to treat wrinkles or soft tissue defects in the body. Over the years, various materials have evolved to correct soft tissue defects, including a number of tissues and polymers. Autogenous dermis, autogenous fat, autogenous dermis-fat, allogenic dermis, synthetic implants, and fillers have been widely accepted for soft tiss...