Dr. Rino Cerio, Prof. E. Wilson Jones, Institute of Dermatology, St. John’s Hospital for Diseases of the Skin, London (UK) Dear Sir, We read with interest the rapid communication by Arrese Estrada and Piérard entitled ‘factorXIIIa-positive dendrocytes and the dermal microvascular unit’ [1]. The authors labelled a variety of benign and malignant skin conditions with factor XΠIa (F-XIIIa) and pro...

Pigmented skin lesion identification is essential for detecting harmful pathologies related to this large organ, especially cancer. An analysis of the different methods and projects developed diagnose these illnesses throughout years showed that they had become very useful tools identify melanoma, dermatofibroma, basal cell carcinoma, among other types cancer, are seen through use new computer-...

OBJECTIVE Dermatofibroma (DF) is a benign fibrohistiocytic tumor whereas dermatofibrosarcoma protuberans (DFSP) has intermediate malignant potential. CD34 is the most commonly used antibody in differentiating these tumors. Various studies have stated the rates of D2-40 expression as 0-50% in DFSPs and 86-100% in DFs. Our aim in this study was to determine the expression of CD34 and D2-40 in DFs...

4. Badalian-Very G, Vergilio J, Degar BA, MacConaill LE, Brandner B, Calicchio ML, et al. Recurrent BRAF mutations in Langerhans cell histiocytosis. Blood. 2010;116:1919--23. 5. Bronwn R, Rieger K, Kim J. 3 Cases of indeterminate cell histiocytosis with an ETV3-NCOA2 translocation. J Cutan Phatol. 2016;43:e56--7. 6. Wollenberg A, Burgdorf WH, Schaller M, Sander C. Long-lasting ‘‘Christmas tree ...

Schwannoma is a benign peripheral nerve sheath tumor. It commonly occurs in head and neck region, upper extremities dorsolumbar spine. The giant schwannoma as such rare occurring We present series of three cases unusual locations, masquerading other soft tissue tumors. : Case 1: A 40-year-old male presented with large exophytic ulcerated growth on his left thigh. lesion was deep dermal location...

Abstract Aim Surgical repair of a complex defect after resection Dermatofibrosarcoma protuberans. Materials-methods: protuberans, is an uncommon soft tissue tumor that involves the dermis, subcutaneous fat, and in rare cases, muscle fascia. We present 49-year-old patient diagnosed with anterior abdominal wall who underwent Mohs surgery to achieve complete resection, resulting 12cmx10cm epigastr...

neous biopsies, yielding 69 collision tumors. Cascajo and colleagues found 54 collision tumors of malignant cutaneous neoplasms associated with seborrheic keratoses in 85,000 biopsies. The most common combinations found by Boyd and Rapini included basal cell carcinoma and nevus (14), basal cell carcinoma and seborrheic keratosis (8), nevus and seborrheic keratosis (14), actinic keratosis and ne...