IMPORTANCE We evaluated 13 distinct patients with multiple telangiectatic pigmented macules confined mostly to the upper arms to determine if the clinical and histopathological features of these cases might represent a specific clinical entity. OBSERVATIONS We retrospectively investigated the clinical, histopathologic, and immunohistochemical features of 13 patients with multiple telangiectat...

Les mastocytoses correspondent à une infiltration tissulaire bénigne de mastocytes dans la peau et éventuellement dans d’autres organes. Les manifestations cliniques des mastocytoses sont variées, et liées en partie aux médiateurs libérés par les mastocytes sur un mode paroxystique. Nous rapportons le cas d’un nourrisson de 9 mois, issu d’un mariage non consanguin, sans antécédents pathologique...

Ashy dermatosis or erythema dyschromicum perstans (EDP) is a typically asymptomatic disease of unknown origin that causes symmetrical gray spots on the trunk and extremities (1). It was first described by Ramirez in 1957 (2). Patients show oval, irregular, or polycyclic gray macules with erythematous, inflammatory borders (3). There is no single established therapy for EDP. The aim of our study...

BACKGROUND Birch pollen is an important outdoor allergen able to aggravate symptoms in atopic dermatitis (AD). Specific immunotherapy (SIT), an established procedure for allergic airway diseases, might also represent an attractive therapeutic option for the causal treatment of allergen-triggered cutaneous symptoms in these patients. Studies with house dust mite SIT have already shown beneficial...

Bloom syndrome is an extremely rare inherited disorder. We present a case of Bloom syndrome with a chromosomal study in a Mexican five-year-old patient who presented growth retardation, narrow facies with poikiloderma, café-au-lait, macules and photosensitivity.

Four new species of the spider genus Ochyrocera Fage, 1912 are described from iron caves in state Minas Gerais, Brazil. Here we present third anophtalmic and depigmented genus, O. dorinha sp. nov. , three other species: monica magali rosinha Only considered as troglobites due ocular reduction or anophthalmia elongated appendages, two troglomorphic features absent described.

Vitiligo is a relatively common acquired skin disorder, characterized by the progressive loss of melanocytes, which results in white patches. Classically, vitiligo’s treatments have been considered unsatisfactory and challenging. Recent advances in the knowledge of vitiligo’s pathogenesis have contributed to find better therapeutic options, so that at present many patients find a solution for d...

To the Editor: Neurofibromatosis type 1 (NF1) is an autosomal dominant, neurocutaneous disorder. In most cases, cutaneous pigmentary manifestations are main diagnostic clue. NF1 characterized by hyperpigmentation—café au lait macules (CALMs), skinfold freckling, and melanotic plexiform neurofibromas. However, hypopigmented lesions have received little attention in patients with NF1. Riccardi1Ri...