Two male rhesus monkeys underwent cyclical feeding of a hypercholesterolemic diet (2% cholesterol, 25% coconut oil) and a low-fat Purina monkey chow diet. During the latter diet, high density lipoprotein (HDL) exhibited two components with peak densities of d = 1.081 g/ml and 1.109 g/ml named HDLL and HDLH, respectively. During the initial hypercholesterolemic stage, except for apo A-II which r...

In a recent paper, we reported that pravastatin sodium (pravastatin), an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme. A reductase, decreases the concentrations of low density lipoprotein (LDL) cholesterol through an LDL receptor pathway in Japanese White (JW) rabbits, whereas this agent lowers high density lipoprotein (HDL) cholesterol in a manner correlated with a reduction of very low de...

1 Full paper 1 Internal Medicine 2 3 Running head: LIPOPROTEIN LIPID CONCENTRATIONS IN DOGS 4 5 Lipoprotein cholesterol and triglyceride concentrations associated with dog body 6 condition score; effect of recommended fasting duration on sample concentrations in 7 Japanese private clinics 8 9 Shiho USUI 1) 17 18 2 ABSTRACT 19 The objectives of this study were to survey clinics' guidance about r...

To test whether estrogen can modulate the cholesterolemic response to an Occidental diet, six healthy postmenopausal women were studied for 84 days while ingesting a solid food diet of constant composition high in cholesterol content (995 mg/d). In the middle of the study, estrogen (17 alpha-ethinyl estradiol, 1 microgram/kg per day) was administered orally. Ingestion of the diet for the initia...

Serum lipid and lipoprotein composition in spontaneously diabetic BB Wistar rats, nondiabetic littermates, and control Wistar rats was studied to elucidate diabetes-related abnormalities of lipoprotein composition. Serum total triglycerides and pre-beta-lipoprotein concentrations of insulin-treated spontaneously diabetic BB and nondiabetic littermate rats were significantly higher than those of...

Objective To evaluate some risk factors for cardiovascular diseases in feeding and eating disorders, the degree of lipid abnormalities was investigated in a large Japanese cohort of different groups of feeding and eating disorders, according to the Japan Atherosclerosis Society Guidelines for the Prevention of Atherosclerotic Cardiovascular Diseases 2012 (JAS Guidelines 2012). Methods Participa...

Plasma and lipoprotein cholesterol and triglyceride concentrations were measured in Pima Indians, a genetically homogeneous population with a high prevalence of obesity and diabetes and a low frequency of coronary heart disease. The data for nondiabetic Pima Indians were compared with those of U.S. Caucasians measured during the Lipid Research Clinics Prevalence Study. Plasma total and low-dens...

1.1. Lipoprotein abnormalities in atherosclerosis, the role of high-density lipoprotein (HDL) The inverse relationship between plasma levels of HDL and coronary heart disease (CHD) has been demonstrated in a number of observational epidemiological studies, such as Framingham Heart Study, and Prospective Cardiovascular Münster Study (PROCAM), as well as in several intervention studies, for examp...

BACKGROUND Decreased high-density lipoprotein (HDL) cholesterol levels constitute a major risk factor for coronary heart disease; however, there are no therapies that substantially raise HDL cholesterol levels. Inhibition of cholesteryl ester transfer protein (CETP) has been proposed as a strategy to raise HDL cholesterol levels. METHODS We conducted a single-blind, placebo-controlled study t...

conclusions this study supports the assumption that low glycemic index diet as well as metformin can positively affect metabolic syndrome components. background metabolic syndrome (mets) continues to be highly prevalent and contributes to a rapidly growing problem worldwide. the most important therapeutic intervention for metabolic syndrome is diet modification, an intervention whose efficacy h...