Although secret sharing techniques have been applied to implement secure electronic sealed-bid auction for a long time, problems and attacks still exist in secret-sharing-based electronic sealed-bid auction schemes. In this paper, a new secret-sharing-based first-bid e-auction scheme is designed to achieve satisfactory properties and efficiency. Correctness and fairness of the new auction are b...

Efficient general secure multiparty computation (MPC) protocols were previously proposed, and the combination with the efficient auction circuits achieves the efficient sealed-bid auctions with the full privacy and correctness. However, the combination requires that each bidder submits ciphertexts of bits representing his bid, and their zeroknowledge proofs. This cost amounts to about 80 multi-...

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the loss of motoneurons in the spinal cord, brainstem and motor cortex. Mutations in the superoxide dismutase 1 (SOD1) gene represent a frequent genetic determinant and recapitulate a disease phenotype similar to ALS when expressed in mice. Previous studies using SOD1(G93A) transgenic mice have suggested a...

Let I be the set of distinct items to be sold in a combinatorial auction, and let N = | I |. The terms auction set and auction size refer to I and N, respectively. Bidders can place bids on any item set, which refers to any non-empty subset of I. A bid b can be represented by the tuple b = (S, v, id). Here S denotes the item set the bid was placed on (∅ ⊂ S ⊆ I), also called the span of the bid...

BACKGROUND Initiation and titration of human regular U-500 insulin (U-500R) with a dosing algorithm of either thrice daily (TID) or twice daily (BID) improved glycemic control with fewer injections in patients with type 2 diabetes treated with high-dose, high-volume U-100 insulin. The objective of this analysis was to compare patient-reported outcomes between U-500R TID and BID treatment groups...

As our world becomes increasingly digitalized, data centers as operational bases for these technologies lead to a consequent increased release of excess heat into the surrounding environment. This paper studies challenges and opportunities industrial symbiosis between centers’ greenhouse farming, specifically utilizing north Sweden case study region. The region was selected in bid tackle urgent...

Bcl-2 family member Bid is subject to autoinhibition; in the absence of stimuli, its N-terminal region sequesters the proapoptotic Bcl-2 homology 3 (BH3) domain. Upon proteolytic cleavage in its unstructured loop, Bid is activated, although structural data reveal no apparent resulting conformational change. We found that, upon Bid cleavage, the N-terminal fragment (tBid-N) is ubiquitinated and ...

Methods enabling the delivery of proteins into eukaryotic cells are essential to address protein functions. Here we propose broad applications to cell biology for a protein delivery tool based on bacterial type III secretion (T3S). We show that bacterial, viral, and human proteins, fused to the N-terminal fragment of the Yersinia enterocolitica T3S substrate YopE, are effectively delivered into...