Background: The aim of this study was to fabricate the poly caprolactone (PCL) aligned nanofiber scaffold and to evaluate the survival, adhesion, proliferation, and differentiation of rat hair follicle stem cells (HFSC) in the graft material using electrospun PCL nanofiber scaffold for tissue engineering applications. Methods: The bulge region of rat whisker was isolated and cultured in DMEM: n...

Tissue engineering is based on three main factors including scaffolds, cells and growth factors. Natural scaffolds derived from decellularized tissues and organs have been successfully used in tissue engineering. Decellularization studies have shown that natural scaffolds which maintaine their main structure and properties could be a suitable tool for studying cellular behaviors and preparation...

Next-generation synthetic bone graft therapies will most likely be composed of resorbable polymers in combination with bioactive components. In this article, we continue our exploration of E1001(1k), a tyrosine-derived polycarbonate, as an orthopedic implant material. Specifically, we use E1001(1k), which is degradable, nontoxic, and osteoconductive, to fabricate porous bone regeneration scaffo...

collagen is the major protein component of cartilage, bone, skin and connective tissue and constitutes the major part of the extracellular matrix. collagen type i has complex structural hierarchy, which consists of treepolypeptide α-chains wound together in a rod-like helical structure. collagen is an important biomaterial, finding many applications in the field of tissue engineering. it has be...

Advances in the additive manufacturing technology have led to the production of complex microstructures with unprecedented accuracy and due todesigning an effective implant is a major scientific challenge in bone tissue regeneration and bone growth. In this research, titanium alloy cylindrical scaffolds with three-dimensional architectures have been simulated and compared for curing partial bon...

regeneration and engineering of functional new tissues containing the neural network have great importance. progression of neural network into the dental tissue has a crucial role in dental tissue regeneration. in the present study polymer-ceramic blended scaffolds containing different weight percentages of carbon nanotube in poly caprolactone nanofiber matrix were fabricated. morphological, me...

A wide range of materials and scaffolding fabrication methods for bone tissue engineering have beenexplored recently. Fiber reinforced polymers (FRP) system appears to be a suitable system. By the exclusiveuse of biocompatible or bio-absorbable polymers and fibers, novel generation of scaffolds for applicationsin tissue engineering can be prepared. Mulberry Silk as highlighted...

in this study, based on a biomimetic approach, novel 3d biodegradable porous hybrid scaffolds consisting of chitosan, gelatin, and tricalcium phosphate were developed for bone and cartilage tissue engineering. macroporous chitosan/ gelatin/β-tcp scaffolds were prepared through the process of freeze-gelation/solid-liquid phase separation. the results showed that the prepared scaffolds are highly...

In this paper an attempt has been made to develop an appropriate storage and collection plan based on optimal routing model using Geologic Information System in one of the wards of the Singanallur, Coimbatore city, India. The ward map is digitized and georeferenced. The collection bins are attributed and collection routes of the MSW are optimized for degradable and recyclable wastes separately....

Considerable efforts have been placed on the development of degradable microspheres for use in transarterial embolization indications. Using the guidance of the U.S. Food and Drug Administration (FDA) special controls document for the preclinical evaluation of vascular embolization devices, this review consolidates all relevant data pertaining to novel degradable microsphere technologies for bl...