Wilson disease is associated with multisystem involvement. We describe a patient of Wilson disease with severe arthropathy, which completely reversed following liver transplantation. This is the first case report in literature describing the complete reversal of Wilson disease related arthropathy by liver transplantation.

Hypertrophic osteo-arthropathy is most commonly associated with bronchopulmonary or pleural diseases. It has also been described in several apparently unrelated conditions and occasionally in patients with no other recognizable disease. The literature is reviewed by Mendlowitz (1942). This paper reports hypertrophic osteo-arthropathy in a patient with polyarteritis nodosa and describes the effe...

BACKGROUND AND OBJECTIVES Osteoarthritis is the most common joint disease among elderly people. This study aimed at comparing the analgesic effects of intra-articular bupivacaine and morphine in knee osteoarthritis patients. METHODS Thirty-nine patients were included in this randomized double-blind study and divided in two groups: G1 (n = 18) patients were given intra-articular 1 mg (1 mL) mo...

OBJECTIVE To investigate the prevalence and pattern of radiographic osteoarthritis (ROA) of the hand joints and its association with self reported hand pain and disability. METHODS Baseline data on a population based study (age >/=55 years) were used (n = 3906). Hand ROA was defined as the presence of Kellgren-Lawrence grade >/=2 radiological changes in two of three groups of hand joints in e...

Abstract Introduction Multilineage differential potentials and immunomodulatory function of mesenchymal stem cells have led to the birth of subfield of regenerative medicine. More than a thousand clinical trials have been conducted, including clinical trials treating joint diseases, e.g. osteoarthritis and inflammatory arthritis. This review is to summarize preclinical studies of mesenchymal st...

joints. Conditions as different as fibromyalgia, scleroderma and gout have often been included with the classic arthritic conditions: osteoarthritis and rheumatoid arthritis. Arthritis is now our nation’s leading cause of disability and is projected by the CDC to effect nearly 60 million Americans (20% of U.S. population) by the year 2020. By far the most prevalent type is osteoarthritis, accou...

For every patient with an anterior cruciate ligament (ACL)-deficient knee combined with degenerative changes, it is important to identify surgical strategies that both optimize ACL reconstruction success and slow degenerative joint disease (DJD) progression. When these surgical strategies are incorporated with a complementary rehabilitation regimen, this patient group has the best possibility f...

Successful treatment of osteoarthritis must effectively control pain, and should slow down or reverse progression of the disease. Biochemical and pharmacological data combined with animal and human studies demonstrate glucosamine sulfate is capable of satisfying these criteria. Glucosamine sulfate's primary biological role in halting or reversing joint degeneration appears to be directly due to...

Osteoarthritis (OA) is the most commonly occurring degenerative joint disease worldwide, and its incidence has increased in recent years. We evaluated whether there is the association between MMP-3 and TIMP-3 variants and susceptibility to OA in a Chinese population. Venous blood samples were collected from 431 female participants (200 cases and 231 controls) at Hong Hui Hospital, Xi'an Jiaoton...

a study was made of interand intra-observer differences in grading hand films for rheumatoid arthritis during the course of therapeutic trials and field surveys. This study indicated that standards used so far in grading x-ray changes for rheumatoid arthritis in field surveys in Leigh and South Wales did not differ greatly from the mean values given by physicians and radiologists in Britain. Be...