In most formulations processed via continuous twin screw granulation microcrystalline cellulose (MCC) and/or lactose are used as excipients, but mannitol is also a preferred excipient for wet granulation and tableting due to its non-hygroscopicity and inertness. Therefore, the aim of the current study was to investigate the influence of process parameters on critical quality attributes of granu...

Behavior genetic approaches are becoming increasingly popular in political science. Many studies, to date, used a classical twin design to explore both political participation and ideological self-placement in Western democracies but studies in different political contexts, such as post-communist countries, are scarce. This paper is the first to explore the heritability of ideology and politica...

A theoretical model for the plastic deformation of calcite, based on symmetry arguments and dislocation theory, is presented. Flow mechanisms suggested by the model conflict with those previously determined by Turner. Predictions from the model include translation gliding on e., ri, f and mI parallel to <110 ( i = 1,2,3; j = 1,2,3,4 ), and twin gliding on r (+) and (-) senses; s = 2.065, 0.630 ...

This paper estimates the causal effect of teenage childbearing on educational attainment using two cohorts of Australian twins and their relatives. Our main finding is that the negative effect of teenage childbearing on educational attainment appears to be small. We find no difference in educational attainment between teen mothers and their identical twin sisters. Data on the relatives of the t...

Focusing on nanocrystalline (nc) pure face-centered cubic metals, where systematic experimental data are available, this paper presents a brief overview of the recent progress made in improving mechanical properties of nc materials, and in quantitatively and mechanistically understanding the underlying mechanisms. The mechanical properties reviewed include strength, ductility, strain rate and t...

Microstructure evolution, dominated by the formation of deformation-induced ?? martensite during 3-point bending a metastable ? Ti–10V–2Fe–3Al alloy containing 5% ?, was observed in-situ using forward-scatter electron imaging and backscattering diffraction. plates nucleated heterogeneously from {580}?? habit planes at ?-? interfaces triggered nucleation additional advancing interface growth upo...

The effect of cold rolling on the microstructure and mechanical properties of an Al- and C-containing CoCrFeNiMn-type high-entropy alloy was reported. The alloy with a chemical composition (at %) of (20-23) Co, Cr, Fe, and Ni; 8.82 Mn; 3.37 Al; and 0.69 C was produced by self-propagating high-temperature synthesis with subsequent induction. In the initial as-cast condition the alloy had an face...

The high hardness or yield strength of an alloy is known to benefit from the presence of small-scale precipitation, whose hardening effect is extensively applied in various engineering materials. Stability of the precipitates is of critical importance in maintaining the high performance of a material under mechanical loading. The long period stacking ordered (LPSO) structures play an important ...

The mechanical properties and plastic deformation mechanisms of metal nanowires have been studied intensely for many years. One of the important yet unresolved challenges in this field is to bridge the gap in properties and deformation mechanisms reported for slow strain rate experiments (∼10-2 s-1), and high strain rate molecular dynamics (MD) simulations (∼108 s-1) such that a complete unders...

In order to investigate the fatigue properties of extruded magnesium alloy in very high-cycle regime, rotary bending fatigue test was performed in ambient atmosphere at room temperature using the hourglass shaped specimens of AZ80 alloys extruded (Fspecimen) and treated by an artificial aging after extrusion (T5-specimen). From the experimental results, both specimens show a clear step-wise S-N...