نتایج جستجو برای: decreased sound tolerance

تعداد نتایج: 619785  

Introduction: Morphine is a potent analgesic but its continual use results in analgesic tolerance. Mechanisms of this tolerance remain to be clarified. However, changes in the functions of μ-opioid and N-Methyl-D-aspartate (NMDA) receptors have been proposed in morphine tolerance. We examined changes in gene expression of the NMDA receptor subunit 1 (NR1) at mRNA levels i...

2011
Luis H. Reyes Maria P. Almario Katy C. Kao

BACKGROUND n-Butanol is a promising emerging biofuel, and recent metabolic engineering efforts have demonstrated the use of several microbial hosts for its production. However, most organisms have very low tolerance to n-butanol (up to 2% (v/v)), limiting the economic viability of this biofuel. The rational engineering of more robust n-butanol production hosts relies upon understanding the mech...

2017
Jian Wang Wei Xu Jiali Shao Zhenghua He Zhuofeng Ding Jiangju Huang Qulian Guo Wangyuan Zou

Morphine tolerance is a clinical challenge in pain management. Emerging evidence suggests that microRNA (miRNA) plays a regulatory role in the development of morphine tolerance. miR-219-5p (miR-219) targets calmodulin-dependent protein kinase II γ (CaMKIIγ) to activate central pain sensitization via N-methyl-D-aspartate (NMDA) receptor. Therefore, we hypothesized that miR-219-5p attenuates morp...

Journal: :Applied and environmental microbiology 1997
L Marron N Emerson C G Gahan C Hill

Exposing Listeria monocytogenes LO28 to sublethal pH induces protection against normally lethal pH conditions, a phenomenon known as the acid tolerance response. We identified a mutant, L. monocytogenes ATR1, which is incapable of inducing such tolerance, either against low pH or against any other stress tested. The virulence of this mutant was considerably decreased, suggesting that the acid t...

Journal: :به زراعی کشاورزی 0
فرهاد عزیزی استادیار، موسسه تحقیقات اصلاح و تهیه نهال بذر، کرج - ایران علی ماهرخ کارشناس، موسسه تحقیقات اصلاح و تهیه نهال بذر، کرج - ایران

in order to comparison and determination of the best drought tolerance indices in sweet corn hybrids, an experiment was conducted using a randomized complete block design in split plot lay out with three replications at seed and plant improvement institute in karaj in 2006. three irrigation levels (irrigation after 75 as control, 100 and 125 millimeters cumulative evaporation from class a evapo...

Journal: :acta medica iranica 0
h. r. jamshidi m. rezayat m. r. zarrindast

in the present study, the effect of apamin (potassium channel blocker) on tolerance to cocaine-induced locomotor activity in mice has been investigated. locomotor activity was measured by locomotor activity meter, animax, type s (lkb, farrad). intraperitoneal (ip) injection of different doses of cocaine (2.5, 5, 10 and 15 mg/kg) produced dose-dependent locomotor activity in mice.animals were tr...

Journal: :بوم شناسی کشاورزی 0
محسن زعفرانیه جعفر ولی زاده سید مسعود ضیایی مجید جعفری محبوبه محسنی بابعبدانی

salinity is one of the environmental factors that have a critical influence on the plant emergence and plant growth and establishment. the determination of salinity tolerance threshold is a useful criterion to choose soil and irrigation water for cultivation of halophytes. in order to determine salinity tolerance threshold in amaranthus retrofelexus, an experiment was performed in greenhouse ba...

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