OBJECTIVE Occurrence of cholangiocarcinoma was recently reported at a high incidence rate among the employees working for an offset printing company in Osaka, Japan. 1,2-Dichloropropane (1,2-DCP) and dichloromethane (DCM) are suspected to be the causes of the cancer, as they had been used as ink cleaners in large amounts. However, it is not clear whether these chlorinated organic solvents playe...

The Disease Control Priorities (DCP) project has substantially influenced national and global health priorities since 1993. DCP’s basic framework involves identification of disease burdens based on premature deaths and disability and application of the most cost-effective interventions to the largest burdens, taking into account local feasibility. The future impact of DCP will need to take into...

The estimation of a large covariance matrix is challenging when the dimension p relative to sample size n. Common approaches deal with challenge have been based on thresholding or shrinkage methods in estimating matrices. However, many applications (e.g., regression, forecast combination, portfolio selection), what we need not but its inverse (the precision matrix). In this paper introduce meth...

OBJECTIVES To assess exposure of commercial application workers to the nematocide cis-1,3-dichloropropene (cis-DCP). METHODS The study was conducted during the annual application season, August to 15 November, in the starch potato growing region in The Netherlands. 14 Application workers collected end of shift urine samples on each fumigation day (n=119). The mercapturic acid metabolite N-ace...

Abstract The imprinted polymers were prepared to absorb dichlorophen (DCP) by using mesoporous silica with ordered pores and high specific surface area. Both scanning electron microscopy transmission results suggested that the nanosphere had a periodic distribution. layer of was thin uniform. adsorption experiments showed obviously improved due presence structure. maximum capacity MSNs@MIPs at ...

To the Editor: We read the manuscript by Lofgren et al. (7) with great interest and would like to compliment them for an excellent comparison and validation of plethysmographic methods to assess airway function in mice. There are two errors that we would like to bring to the authors’ notice. First, the units of specific airway resistance (sRaw) should be cmH2O s not cmH2O/s {sRaw Raw TGV (press...