Hot-stage/Fourier transform infrared microspectroscopy (FTIR-M) was used to determine the diffusivities of a series of dialkyl phthalates in poly(viny1 butyral) (PVB) spin-coated films. The diffusivities ranged from lo-'' to lo-'' cmz/s for the isotherms investigated (60" to 150°C). In their respective temperature regimes, dimethyl phthalate and diethyl phthalate exhibited nonlinear diffusion b...

The multifunctional DNA-binding protein (DBP) encoded by human adenovirus binds RNA. The association of purified DBP with RNA in vitro was demonstrated by using either a gel filtration or a filter binding assay. This association is sensitive to ionic strength and exhibits no apparent sequence specificity. DBP also interacts with RNA in vivo; it can be crosslinked to polyadenylylated RNA by UV-i...

Although systolic blood pressure (BP; SBP) is the best predictor of future cardiovascular disease (CVD) risk for the majority of the older hypertensive population, there is much that can be learned from simultaneously assessing diastolic BP (DBP) and its relation to levels of SBP.1 After 50 years of age, SBP increases disproportionately to DBP, and after 60 years of age DBP falls, resulting in ...

In point-to-point networks, real-time services are supported by sending real-time streams over guaranteed or best-effort channels [1]. A stream consists of packets moving across individual links on the point-topoint network from a given source to destination. For each link, a scheduler is responsible for determining which packets shall be transmitted according the queue of packets stored. For s...

TThe National Toxicology Program (NTP) Center for the Evaluation of Risks to Human Reproduction (CERHR) conducted an evaluation of the potential for di-n-butyl phthalate (DBP) to cause adverse effects on reproduction and development in humans. DBP is one of 7 phthalate chemicals evaluated by the NTP CERHR Phthalates Expert Panel. These phthalates were selected for evaluation because of high pro...

BACKGROUND Observational studies have shown that vitamin D binding protein (DBP) levels, a key determinant of 25-hydroxy-vitamin D (25OHD) levels, and 25OHD levels themselves both associate with risk of disease. If 25OHD levels have a causal influence on disease, and DBP lies in this causal pathway, then DBP levels should likewise be causally associated with disease. We undertook a Mendelian ra...

We measured the free concentration of 1,25-dihydroxyvitamin D (1,25[OH]2D) using centrifugal ultrafiltration, and the level of vitamin D-binding protein (DBP) in 24 normal subjects, 17 pregnant subjects, and 25 alcoholic subjects with liver disease. Our objective was to determine whether the increase in total 1,25(OH)2D levels in pregnant women and the reduction in total 1,25(OH)2D levels in su...

Vitamin D binding protein (DBP), also known as the group-specific component of serum (Gc-globulin), is a member of the albumin, α-fetoprotein, and α-albumin multigene family (1, 2). DBP is a highly polymorphic serum protein predominantly synthesized in the liver as a single-chain glycoprotein of ∼58 kDa (3). The serum concentration of human DBP is 4–8 μΜ and its serum halflife is 2.5–3 days. DB...

Di-n-butyl phthalate (DBP) is an endocrine-disrupting chemical that has the potential to affect male reproduction. However, the reproductive effects of low-dose DBP are still not well known, especially at the molecular level. In the present study, pubertal male Sprague-Dawley rats were orally administered DBP at a wide range of doses (0.1, 1.0, 10, 100 and 500 mg kg⁻¹ day⁻¹) for 30 days. The se...

BACKGROUND AND OBJECTIVES The J-curve phenomenon between diastolic blood pressure (DBP) and mortality has been reported repeatedly in treated patients. However, the baseline risk of low DBP has not been fully explored. This study was to examine the relationship between DBP and risk of mortality from all-cause, atherosclerotic vascular diseases (ASCVD), and ischemic heart disease (IHD) using a p...