O'Dea, B., Lee, R., McGorry, P., Hickie, I., Scott, J., Hermens, D., Mykeltun, A., Purcell, R., Killackey, E., Pantelis, C., Glozier, N., et al (2016). A prospective cohort study of depression course, functional disability, and NEET status in help-seeking young adults. Social Psychiatry and Psychiatric Epidemiology, 51(10), 1395-1404. [More ...

Daniel Aaronson is an economist and Daniel G. Sullivan is a senior economist and vice president at the Federal Reserve Bank of Chicago. The authors would like to thank Ann Ferris for her very capable assistance.

When Daniel Janzen gave his acceptance speech for the 1997 Kyoto Prize, he disappointed many people who had come to hear a preeminent biologist discuss iconic studies, from ant–acacia mutualism to seed predation (1, 2). “They expected a talk about science, but I’d switched to conservation,” explains Janzen, DiMaura Professor of Conservation Biology at the University of Pennsylvania. Janzen, who...

Protein docking protocols are used for the prediction of both small molecule binding to DNA and protein macromolecules and of complexes between macromolecules. These protocols are becoming increasingly automated and powerful tools for computer-aided drug design. We revew the basic methodologies and strategies used for analyzing molecular recognition by computer docking algorithms and discuss re...

My research over the past decade has focused on problems at the intersection of Algorithms and Combinatorics with Optimization, Scientific Computation and Engineering. In my work, I develop mathematically rigorous analyses of algorithms and heuristics used to solve fundamental computational problems. I then try to use these analyses to obtain insight into how these problems can be better solved...

Treatments for brain dysfunction have relied traditionally on medication-based approaches. Non-invasive transcranial electric stimulation (tES) approaches such as transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS) offer an alternative approach for psychiatric treatment. In this approach, low level (1–2 mA) currents are applied over appropriate...

Möbius is an extensible framework and tool for performance and dependability modeling, and supports multiple modeling formalisms and solvers. As a framework, Möbius must be sufficiently general to capture the various formalism behaviors. Specifically, the Möbius execution policy must be flexible enough to accommodate the execution policies of all formalisms implemented in the framework. We know...

In this paper we describe an operation on directed graphs which produces a graph with fewer vertices, such that the C-algebra of the new graph is Morita equivalent to that of the original graph. We unify and generalize several related constructions, notably delays and desingularizations of directed graphs.