BACKGROUND Low-molecular-weight heparins (LMWH) have been shown to be safer, more effective and more convenient than unfractionated heparin (UFH) in many clinical situations. However, their use is limited in patients with renal insufficiency (RI) due to bioaccumulation. METHOD The literature is critically reviewed and known pharmacokinetic properties are summarised. An approach to using LMWH ...

This study investigates the impact of an interactive television public-service announcement (PSA) containing an anti-speeding threat appeal on feelings of telepresence and behavioral intention. In a 2 × 2 × 2 between-subjects factorial design with 213 participants, the level of threat evoked by a traditional PSA, by the interactive part of the PSA (dedicated advertising location or DAL) and by ...

BACKGROUND In Canada, there is a dose cap for weight-based treatment with low-molecular-weight (LMW) heparins. OBJECTIVE To review whether capping of LMW heparin doses is warranted for patients with obesity. METHODS English-language publications concerning the use of LMW heparin in Canada were reviewed, and the literature regarding use of these drugs at treatment doses in patients with obes...

BACKGROUND Venous thromboembolism (VTE) is a common complication after stroke. Application of low molecular weight heparins (LMWH) has been proven to be beneficial for the prevention of VTE in ischemic stroke patients. However, there is no consensus whether and how to administer LMWH for prevention of thrombotic complications after acute spontaneous intracerebral hemorrhage (sICH), the main con...

Abstract: Low-molecular-weight heparins (LMWHs) have proven to be effective in the prevention and treatment of thrombotic disorders, as well substitute for unfractionated heparin (UFH). LMWHs are a diverse collection medicines with different biochemical pharmacological characteristics, despite fact that they all antithrombotic actions. Medicine is administered into subcutaneous tissues these in...

OBJECTIVE Patients undergoing total hip replacement (THR) are at high risk of venous thromboembolism (VTE) and according to guidelines they should receive pharmacological prophylaxis. We would like to compare the efficacy, adherence and safety of dabigatran and low molecular weight heparins (LMWH) for the prevention of VTE in patients who underwent THR. PATIENTS AND METHODS This study enrolle...

AIMS The excretion of low molecular weight heparin (LMWH) in breast milk was investigated in 15 lactating mothers after Caesarean section. METHODS Blood and milk samples were collected before and 3-4 h after once daily routine subcutaneous injection of 2500 IU dalteparin. Anti-Xa activity was measured by an assay utilizing prolonged clotting times in plasma or breast milk as an index of LMWH ...

1 2 AN AUDITORY COLLICULO-THALAMOCORTICAL BRAIN SLICE PREPARATION IN MOUSE 3 4 5 Daniel A. Llano, Bernard J. Slater, Alexandria M.H. Lesicko, Kevin A. Stebbings 6 7 8 1. Department of Molecular and Integrative Physiology, UIUC 9 2. Beckman Institute, UIUC 10 3. Neuroscience Program, UIUC 11 4. College of Medicine, University of Illinois 12 13 Acknowledgements: This work was partially supported ...