Insect responses that are specific for virus infection have been investigated using the genetically tractable Drosophila melanogaster. Most studies focus on interactions with Drosophila C virus (DCV), which is a member of the family Dicistroviridae. DCV is a non-enveloped, T=3 icosahedral virus with a positive-sense RNA genome. It was demonstrated recently that several genes controlled by the J...

A comparison of the daclatasvir (DCV [BMS-790052]) resistance barrier on authentic or hybrid replicons containing NS5A from hepatitis C virus (HCV) genotypes 1 to 6 (GT-1 to -6) was completed using a replicon elimination assay. The data indicated that genotype 1b (GT-1b) has the highest relative resistance barrier and genotype 2a (GT-2a M31) has the lowest. The rank order of resistance barriers...

The effective use of nursing diagnosis internationally depends in part on incorporating language and cultural difference into the common language of nursing. International validation studies can provide a basis for this effort. This study tested three diagnoses--anxiety, hopelessness, and ineffective airway clearance--through multinational validation. The Diagnostic Content Validity (DCV) model...

Fluid transport through microporous carbon-based materials is inherent in numerous applications, ranging from gas separation by carbon molecular sieves to natural gas production from coal seams and gas shales. The present study investigates the steady-state permeation of supercritical methane in response to a constant cross-membrane pressure drop. We performed dual control volume grand canonica...

Carbon-dioxide (CO2) based demand controlled ventilation (DCV) offers the potential for more energy efficient building ventilation compared with constant ventilation rates based on design occupancy. A number of questions related to CO2 DCV exist regarding energy benefits, optimal control strategies, and indoor air quality impacts for contaminants with source strengths that are independent of th...

A novel method is presented for the beam shaping of far field intensity distributions of coherently combined fiber arrays. The fibers are arranged uniformly on the perimeter of a circle, and the linearly polarized beams of equal shape are superimposed such that the far field pattern represents an effective radially polarized vector beam, or discrete cylindrical vector (DCV) beam. The DCV beam i...

Decadal climate variability (DCV) has impacted society for centuries, perhaps millennia. There are well-documented episodes of droughts, floods, and tropical storms lasting one or more decades in many parts of the world. It was believed for many centuries that solar and lunar cycles at decadal timescales (~10-20 years) influence the Earth’s climate. This belief led to the development of concept...

A rapid method to parameterize the intramolecular component of classical force fields for complex conjugated molecules is proposed. The method is based on a procedure of force matching with a reference electronic structure calculation. It is particularly suitable for those applications where molecular dynamics simulations are used to generate structures that are therefore analysed by electronic...

Three new triarylborane conjugated dicyanovinyl chromophores (Mes2B-π-donor-DCV); donor: N-methyldiphenylamine () and triphenylamine ( and [with two BMes2 substitutions]) of type A-D-A (acceptor-donor-acceptor) are reported. Compounds exhibit intense charge transfer (CT) absorption bands in the visible region. These absorption peaks are combination CT bands of the amine donor to both the BMes2 ...