Millions of people living in rural areas of Sub-Saharan Africa supplement earnings from subsistence farming by operating microenterprises or by working as day laborers. However, little is known about how people choose which of these additional incomegenerating activities to do, and, in particular, to what extent market imperfections affect this choice and contribute to inefficiencies in product...

Increases in uncertainty have ambiguous effects on the rate of investment in complete contracts models. Consequently, in order to model the adverse effects of high inflation on capital accumulation, macro models overimpose a CIA constraint to buy capital goods. The fall in investment is thus due to an increase in the effective price of capital goods, and not due to inflation uncertainty. In inc...

a r t i c l e i n f o JEL classification: H25 E22 D92 Keywords: Corporate taxation Capital accumulation User cost of capital We present new empirical evidence that sector-level capital–output ratios are strongly influenced by corporate tax incentives, as summarised by the tax component of a standard user cost of capital measure. We use sectoral panel data for the USA, Japan, Australia and eleve...

We show how labour market restrictions, such as firing costs, and bail-outs may arise as useful institutions to support investment in specific human capital. The specificity of human capital is determined endogenously. While specific human capital is more productive than the general human capital, it cannot be reallocated across industries. Accordingly, the optimal fraction of individuals with ...

Background: Reprogramming of cellular metabolism is one the hallmarks cancer (Hanahan, 2022), thus representing an important therapeutic target. 3-bromopyruvate (3BP or KAT/3BP) a small, highly reactive molecule formed by bromination pyruvate (Ko et al, 2012). The very high similarity its structure with pyruvic acid and lactic basis mechanism action as anti-cancer agent. Indeed, 3BP enters cell...

a r t i c l e i n f o JEL classifications: F13 L42 L13 D92 Keywords: price discrimination investment parallel trade pharmaceuticals net neutrality We examine a model of a monopolist selling to two segments of consumers with different preferences for quality. We show that if the firm is unable to price discriminate between the segments, then there is less investment in quality. We find that both...

CPl (encoded by the CEPl gene) is a centromere binding protein of Saccharomyces cerevisiae that binds to the conserved DNA element I (CDEI) of yeast centromeres. To investigate the function of CP1 in yeast meiosis, we analyzed the meiotic segregation of CEN plasmids, nonessential chromosome fragments (CFs) and chromosomes in cepl null mutants. Plasmids and CFs missegregated in 10-2076 of meiose...

When individual petroleum-producing Þrms make their exploration and development investment timing decisions, positive information externalities and negative extraction externalities may lead them to interact strategically with their neighbors. This paper examines whether these inefficient strategic interactions take place in U.S. federal lands in the Gulf of Mexico. In particular, it analyzes w...

Bacteriophage λ protein phosphatase (λPP) with Mn2+ as the activating metal cofactor was studied using phosphatase inhibition kinetics and electron paramagnetic resonance (EPR) spectroscopy. Orthophosphate and the oxoanion analogues orthovanadate, tungstate, molybdate, arsenate, and sulfate were shown to inhibit the phosphomonoesterase activity of λPP, albeit with inhibition constants (Ki) that...