4-Deuterioglutamic acid was prepared by incubation in DzO of ammonium mesaconate with an extract of Clostri&urn tetanomorphum. In these extracts, methylaspartase catalyzed the formation of threo-3-methyl-L-aspartate-3-D, which was then rearranged to glutamate by the cobamide coenzyme-dependent glutamate mutase. The monodeuteriosuccinate obtained by chloramine-T oxidation of the glutamate showed...

A new peptide antibiotic complex B-43, active against Gram-positive and Gram-negative bacteria, was isolated from a strain of Bacillus circulans. This antibiotic contains aspartic acid, valine, isoleucine, leucine, phenylalanine and 2,4-diaminobutyric acid. It seems to be related to polypeptin and antibiotic complex 4205, but differs in that it contains aspartic acid residue.

The study was conducted to determine the influence of D-aspartic acid (D-Asp) as antioxidant supplement and thawing rates on ram sperm motility, membrane integrity, abnormality, viability, mitochondria activity, malondialdehyde and antioxidant activities, and total antioxidant capacity after freezing-thawing process. Semen samples from five mature rams (3-4 years old) were diluted with extender...

A preceding paper described the characteristics of the isolated enzyme system, prepared from ox liver acetone powder, which catalyzes the conversion of citrulline and aspartic acid to arginine and malic acid. It was shown that the fundamental requirements for arginine synthesis from citrulline are aspartic acid, Mg++, and adenosine triphosphate (ATP), the latter as a reactant in substrate conce...

Wzx belongs to a family of membrane proteins involved in the translocation of isoprenoid lipid-linked glycans, which is loosely related to members of the major facilitator superfamily. Despite Wzx homologs performing a conserved function, it has been difficult to pinpoint specific motifs of functional significance in their amino acid sequences. Here, we elucidate the topology of the Escherichia...