نتایج جستجو برای: cytotoxicity activity
تعداد نتایج: 1164261 فیلتر نتایج به سال:
The objective of the current study was to systematically review the in-vitro anticancer activity of green synthesized gold nanoparticles (AuNPs) against hepatic cancer cells. The articles were identified through electronic databases, including PubMed, Scopus, Embase, Web of Science, Science Direct, ProQuest, and Cochrane. In total, 20 articles were found eligible to enter into our syst...
A series of indole-based aryl(aroyl)hydrazone analogs of antiplatelet indole-3-carboxaldehyde phenylhydrazone were synthesized by the Schiff base formation reaction and their antiplatelet activity was assessed using human platelet rich plasma. The platelet concentrate was obtained using a two-step centrifugation protocol and ADP, arachidonic acid and collagen were used as inducers of platelet a...
Received: 3 April, 2009 Accepted: 5 Oct, 2009 Abstract Background & Aim: Nowadays, different medical approaches are used for the treatment of cancers, but in most cases they are not effective or have serious side-effects. This has prompted scientists to look for more effective drugs with less toxicity. This study was to evaluate the cell cytotoxicity effect of fractions isolated from Pleurotu...
Xestoquinone and related metabolites (the xestoquinone family) occur in marine sponges and are known to show a variety of biological activities. In this study, the first comprehensive evaluation of antifungal activity was performed for xestoquinone and nine natural and unnatural analogues in comparison with their cytotoxicity. The cytotoxicity against two human squamous cell carcinoma cell line...
Fourteen semisynthetic compounds derived from the natural scopadulane-type diterpenes thyrsiflorin A (4), B (5), and C (6), including several precursors, have been examined in vitro for their antiherpetic activity against Herpes simplex virus type II (HSV-2) and cytotoxicity against two human tumor cell lines. Four of these compounds showed moderate antiherpetic activity, but none of them exhib...
Diarylpentanoids exhibit a high degree of anti-cancer activity and stability in vitro over curcumin prostate cancer cells. Hence, this study aims to investigate the effects diarylpentanoid, 1,5-bis(4-hydroxy-3-methoxyphenyl)-1,4-pentadiene-3-one (MS13) on cytotoxicity, anti-proliferative, apoptosis-inducing, anti-migration properties, underlying molecular mechanisms treated androgen-independent...
Murraya paniculata (MP) can be used as a reducing agent to produce silver nanoparticles (AgNPs) using simple procedure. AgNPs are characterized in morphological and chemical properties, antioxidant activity, cytotoxicity. The morphology of derived from MP shows face-centered cubic structure, spherical shape with an average particle size 23 nm. structure characteristic peaks UV-vis spectrometer ...
sea algae are widely consumed in the world. there are several seaweeds including brown algae which are authorized for human consumption. these plants contain important phytochemical constituents and have various potential biological activities. the present study investigated the presence of phytochemical constituents and total phenolic quantity of the seaweeds sargassum angustifolium , sargassu...
Purpose: To evaluate the leishmanicidal and cytotoxic activity of alcohol and non-alcohol extracts and saponins from Ilex laurina. Methods: Extracts were obtained by percolation with solvents of different polarities: hexane, dichloromethane, ethyl acetate and ethanol. The ethyl acetate extract was subjected to silica gel column chromatography eluting with a step gradient of dichloromethane-meth...
improving the solubility of non-soluble herbal materials is an issue of interest in cell culture based experiments. evaluating the biological activity of these materials could become possible with the aid of cosolvents/surfactants which obviously should have little or no cytotoxic activity. in the present study, the cytotoxic activity of six cosolvents/surfactants: ethanol, methanol, tween 20 a...
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