نتایج جستجو برای: cysteamine
تعداد نتایج: 950 فیلتر نتایج به سال:
P-glycoprotein (P-gp) is an ATP-dependent transporter localized at the apical membrane of the kidney proximal tubules, which plays a role in the efflux of cationic and amphipathic endogenous waste products and xenobiotics, such as drugs, into urine. Studies in mice deficient in P-gp showed generalized proximal tubular dysfunction similar to the phenotype of patients with cystinosis, an autosoma...
BACKGROUND Cysteamine has improved survival and prognosis in cystinosis. Increasing numbers of patients reach adulthood and face new challenges such as compliance that wanes over time. The aim of this study was to evaluate adherence to cysteamine treatment in a group of cystinotic patients in Spain in an attempt to identify potential therapy pitfalls and improve the overall care of affected ind...
A universal and label-free photoelectrochemical cytosensing strategy was designed based on resonance energy transfer (RET) between carbon dots and cysteamine capped gold nanoparticles. RET promoted photo-to-current conversion efficiency and enhanced detection sensitivity. This proposed photoelectrochemical cytosensing platform exhibited a good performance for the assay of tumor cells with overe...
CdTe nanocrystals capped by cysteamine were synthesized to study Cr(V)-induced genotoxicity. On the surface of TiO2 thin films, the stepwise process of DNA breakage induced by Cr(V)-GSH complexes was vividly observed by using CdTe-DNA self-assembled fluorescent probes; in acetate buffer solution, an analytical method was developed to detect Cr(V)-induced genotoxicity with CdTe fluorescent probes.
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