نتایج جستجو برای: cycloheximide

تعداد نتایج: 4646  

Journal: :Chemical and Pharmaceutical Bulletin 1972

Journal: :Cancer research 2007
Liyue Zhang Anil Wali Chilakamarti V Ramana Arun K Rishi

Human breast cancer (HBC) cell growth suppression by okadaic acid (OA) was previously found to involve elevated expression of oncogenes c-myc and c-fos and apoptosis. Since, c-Myc influences diverse pathways of cell growth, we hypothesized that elevated levels of c-Myc are involved in HBC growth suppression. Here, we investigated whether induction of c-Myc by OA or protein synthesis inhibitor c...

Journal: :The Journal of pharmacology and experimental therapeutics 2008
Valerie Croons Wim Martinet Arnold G Herman Guido R Y De Meyer

Recent evidence indicates that the protein synthesis inhibitor cycloheximide triggers selective macrophage death in rabbit atheroma-like lesions without affecting smooth muscle cells (SMCs) or the endothelium, thereby favoring a stable plaque phenotype. In this study, we report that puromycin, a protein synthesis inhibitor with a different mode of action but with similar ability to inhibit de n...

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