OBJECTIVES Patients with cyanotic congenital heart disease are generally thought to be limited by hypoxemia. To correlate exercise tolerance to the severity of the cardiac abnormality and to further characterize dyspnea in affected patients, we examined 25 adults with uncorrected cyanotic congenital heart disease. DESIGN AND SETTING Cohort study at a university hospital. METHODS Symptom-lim...

Adults with polycythaemia secondary to cyanotic congenital heart disease may be at greater risk from injudicious venesection than from their polycythaemia. Despite an established literature on the subject, patients are frequently put at risk from acute volume depletion and chronic iron deficiency. This article aims to clarify some of the issues surrounding venesection and to set out guidelines ...

Objective—To evaluate changes in cognitive and academic functioning following cardiac surgery in children with congenital heart disease. Design—A prospective cross sectional study in which patients were assessed immediately before treatment and 12 months later. Patients—Three groups of children aged 3.5–17 years: a group with congenital heart disease awaiting surgery, another awaiting bone marr...

AIMS To evaluate the relative effect of cyanosis, surgical interventions and family processes on neuropsychological and behavioural outcomes in 4-year-old survivors of serious congenital heart disease (CHD). METHODS 90 children with a range of cyanotic and acyanotic conditions, who underwent either corrective or palliative surgery, completed a neuropsychological and behavioural evaluation. Fa...

William E. Hopkins, Zengyi Chen, Naomi K. Fukagawa, Christian Hall, Harm J. Knot and Peptide Secretion Disease : Enhanced Understanding of the Relationship Between Hypoxia and Natriuretic Increased Atrial and Brain Natriuretic Peptides in Adults With Cyanotic Congenital Heart Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2004 American Heart Association, Inc. All rights reserved. is ...

BACKGROUND Cerebral abscess is a serious life threatening complication of several diseases. The objective of this study was to look at the clinical profile, microbiology and outcome of children with cerebral abscess having an underlying congenital heart disease as compared to other predisposing conditions. METHODS Thirty children aged less than 15 years were reviewed. There were 15 males and ...