In the Gilbert–Shannon–Reeds shuffle, a deck of N cards is cut into two approximately equal parts which are riffled together uniformly at random. Bayer and Diaconis (Ann. Appl. Probab. 2 294–313) famously showed that this Markov chain undergoes cutoff in total variation after 3log(N) 2log(2) shuffles. We establish for more general asymmetric riffle shuffles one cuts differently sized parts. The...

Molecular size is one of the key determinants of transvascular transport of therapeutic agents in tumors. However, there are no data in the literature on the molecular size dependence of microvascular permeability in tumors. Therefore, we measured microvascular permeability to various macromolecules in the human colon adenocarcinoma LS174T transplanted in dorsal skin chambers in severe combined...

OBJECTIVE To predict the percent body fat (%BF) cutoff values corresponding to overweight and obesity recommended by the International Obesity Task Force (IOTF) in Korean children and to compare those values with the published cutoff values in Caucasian children. RESEARCH METHODS AND PROCEDURES The sample consisted of 1083 Korean children and adolescents (555 boys and 528 girls) aged 7-18 yea...

SC) is a characteristic type of SC with increased serum IgG4 levels and dense infiltration of IgG4-positive plasma cells with extensive fibrosis in the bile duct wall.1 IgG4-SC is now recognized within the spectrum of systemic IgG4-related diseases. IgG4-SC is well resolved by steroid therapy, which is a characteristic feature of IgG4-related disease. IgG4-SC is frequently associated with type ...

We report RBC and RBC/UKQCD lattice QCD numerical calculations of nucleon electroweak matrix elements with dynamical domain-wall fermions (DWF) quarks. The first, RBC, set of dynamical DWF ensembles employs two degenerate flavors of DWF quarks and the DBW2 gauge action. Three sea quark mass values of 0.04, 0.03 and 0.02 in lattice units are used with 220 gauge configurations each. The lattice c...

Accurate detection and removal of infected cattle, using immunodiagnostic tests such as the comparative intradermal tuberculin (CIDT) test, are the basis of control strategies for bovine tuberculosis (TB). According to the Office des Internationale Epizooties recommendation, the cutoff point for positivity of the CIDT test, calculated as the difference between skin thicknesses after bovine tube...

We introduce a new, high-throughput, synchronous, distributed, data-parallel, stochasticgradient-descent learning algorithm. This algorithm uses amortized inference in a computecluster-specific, deep, generative, dynamical model to perform joint posterior predictive inference of the mini-batch gradient computation times of all worker-nodes in a parallel computing cluster. We show that a synchro...