Aleukemic leukemia cutis is a rare condition characterized by the infiltration of the skin by leukemic cells before their appearance in the peripheral blood or bone marrow. We report here a 62-year-old seemingly healthy patient who presented with disseminated erythematous maculae. A skin biopsy showed leukemia cutis of monocytic type. No involvement of bone marrow or peripheral blood was found....

amyloidosis cutis dyschromica (acd) is a rare form of macular amyloidosis characterized by hypo and hyperpigmented macules. here we described a 20 year old girl with diffuse hypo and hyperpigmentation since she was four years old. five other members of her family are also involved. biopsy of hyperpigmented lesions revealed increase of melanin in the basal layer, pigment incontinence and amorpho...

Acanthosis nigricans is characterized by papillomatous brownish lesions mainly in the intertriginous areas. We used dermoscopy to examine such lesions in a family with acanthosis nigricans. The dermoscopic images showed an aberrant skin structure of linear crista cutis and sulcus cutis, and hyperpigmented dots in crista cutis. The hyperpigmented dots, which could not be seen with the naked eyes...

Calcinosis cutis is a rare condition characterized by the deposition of insoluble calcium salts in the skin and subcutaneous tissue. Dystrophic calcinosis cutis appears as a result of local tissue damage or abnormalities, such as alterations in extracellular matrix proteins or subcutaneous tissue with normal calcium and phosphate serum levels. It has been rarely described as a late complication...

8. Koizumi H, Kumakiri M, Ishizuka M, Ohkawara A, Okabe S. Leukaemia cutis in acute myelomonocytic leukaemia: infiltration of minor traumas and scars. J Dermatol. 1991;18:281--5. 9. Kristensen IB, Moller H, Kjaershov MW, Yderstraede K, Moller MB, Bergmann OJ. Myeloid sarcoma developing in pre-existing pyoderma gangrenoso. Acta Derm Venereol. 2009;89:175--7. 10. Guinovart RM, Carrascosa JM, Ferr...

The most widely accepted classification of calcinosis cutis is reviewed and several aspects of it are examined. The main point of our criticism is that entities from different groups overlap. Also, the classification mixes etiopathogenic criteria with morphological or semiologic ones. Moreover, the role of the dermatopathologist is limited many times, since only generic information under the di...

Amyloidosis cutis dyschromica (ACD) is a rare form of macular amyloidosis characterized by hypo and hyperpigmented macules. Here we described a 20 year old girl with diffuse hypo and hyperpigmentation since she was four years old. Five other members of her family are also involved. Biopsy of hyperpigmented lesions revealed increase of melanin in the basal layer, pigment incontinence and amorpho...

Calcinosis cutis is an uncommon soft tissue lesion characterized by the deposition of calcium salts in skin or subcutaneous attributed to a wide variety causes. We present case idiopathic calcinosis adult male, who presented with swelling right iliac region. Chalky white aspirate and amorphous basophilic granular material on microscopy suggestive deposits were noted. Histopathological examinati...

Cutis laxa, clinically characterized by loose and pendulous skin related to loss of elastic tissue, is a rare heterogeneous condition. It is classified into congenital and acquired types. We report a case of generalized acquired cutis laxa type 1 in a young man following pruritic urticarial plaques. We have done a brief review of literature.

Sir, Lymphocytoma cutis of Spiegler-Fendt type is a rare chronic B lymphocyte proliferation a¡ecting the head and the neck in particular. It is characterized by solitary or grouped nodules or plaques which are purple or red and may reach a diameter of 3 ^ 5 cm. Although lymphocytoma cutis is a benign disorder, it often runs a protracted, even life-long course. Progression to malignant B cell ly...