background: leishmania is a significant health problem in many parts of the world. tumor necrosis factor (tnf) plays an essential role in leishmania major infections. objective: to study the pro-inflammatory cytokines and antioxidants in four groups of cutaneous leishmaniasis patients. methods: 39 patients were divided into four groups of: 1) active (acute phase of treatment); 2) non-healing (r...

background: the effect of several probiotics on diseases of the gastrointestinal tract, including gastric ulcers is well reported. however, there are limited numbers of studies assessing the impact of bacillus subtilis (b. subtilis) probiotic on skin wound healing. m aterials and methods: fifty male rats were assigned to 3 different groups randomly. a 1.5 cm longitudinal full thickness incision...

in view of the finding of several cases of cutaneous leishmaniasis in some areas of khuzestan southern iran and the absence of information about its sandfly fauna,  this study was undertaken to elucidate the entomological and whenever possible, the epidemiological aspects of this disease in this province. in these studies more than 21,000 specimens were collected and identified we found eleven ...

conclusions decreasing trend during recent six years reflects a partial success in leishmaniasis control, but update data regarding geographical cl distribution can guide our intervention effectively. results during our six years study, we observed a significant decreasing incidence trend. totally, 2863 cl cases were registered. risk of disease in men was 1.4 times more than women and in rural ...

background : leishmaniasis is one of the infectious parasitic diseases of highest incidence in the world. cutaneous leishmaniasis (cl) has long been reported in shiraz, southern iran. there is a need to find a sensitive and specific method for treatment and control of the disease. methods: we have compared the sensitivity of the conventional methods microscopy and cultiva­tion of lesion scrapes...

background: an epidemiological study was carried out on the vector(s) and reservoir(s) of cutaneous leishmaniasis in rural areas of kalaleh district, golestan province during 2006 - 2007. methods: totally 4900 sand flies were collected using sticky papers and were subjected to molecular methods for de­tection of leishmanial parasite. results: phlebotomus papatasi was the common species in outdo...

background and purpose: detection of agents responsible for cutaneous mycosis may be effective in the prevention of fungal infections from environmental and animal sources. with this background in mind, in this study, we aimed to identify the distribution of cutaneous mycotic infections in patients referred to imam reza hospital of mashhad, iran during 2000- 2011. materials and methods: in tota...

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The ability of antibodies in bloodmeals of mice and hamsters immunized with Leishmania major subcellular fractions and sandfly (Phlebotomus duboscqi) gut antigens to inhibit development of L. major in its vector P. duboscqi was examined. Antibodies from animals immunized with either L. major subcellular fractions alone or sandfly gut antigen alone were not very effective in inhibiting developme...

Several species of the subgenus Psychodopygus Mangabeira, 1941 are known to be leishmaniosis vectors in Brazil. Some of them are morphologically similar, which makes their identification quite difficult concerning epidemiological studies. The aim of the current work is to study the morphology of adult specimens of the subgenus Psychodopygus, in accordance with the morphological similarity and s...