Cutaneous metastases from internal malignancies are uncommon and occur in 0.6%-10.4% of all patients with cancer. In most cases, cutaneous metastases develop after the initial diagnosis of the primary internal malignancy and late in the course of the disease. Skin tumors are infrequent in Asian population and cutaneous metastases are quite rare. Cutaneous metastases carry a poor prognosis with ...

BACKGROUND Immunosuppression for solid organ transplantation is associated with increased incidence of internal and cutaneous malignant tumors, among which skin cancer is the most common. OBJECTIVE To determine the effects on cutaneous carcinogenesis when stopping therapy with immunosuppressive medications. OBSERVATIONS We followed the clinical course of 6 solid organ transplant recipients ...

BACKGROUND Several epidemiological studies have suggested an association between cutaneous melanoma and non-Hodgkin's lymphoma. METHODS We pooled the data from seven cohort studies and calculated the risk of secondary occurrence of cutaneous melanoma after non-Hodgkin's lymphoma, and of non-Hodgkin's lymphoma subsequent to the occurrence of cutaneous melanoma. RESULTS There were 137 612 pat...

background: considering the prevalence of leishmaniasis in iran and many side effects associated with pentavalent antimony compounds use in its treatment, this study was designed to evaluate the effect of artemisia sieberi essence on the experimental ulcers of cutaneous leishmaniasis on balb/c mice. methods: this experimental research was performed to determine the effect of various concentrati...

introduction: cutaneous leishmaniasis (cl) is a widespread disease that is epidemic in iran, too. photodynamic therapy (pdt) is an attractive modality to treat cancer and hyper proliferative diseases based on the use of a photosensitizer in the presence of oxygen and proper wavelength of light. in consideration of lesion location, lack of systemic involvement and inefficiency of current treatme...

background: leishmania homologue of receptors for activated c kinase(lack) antigen is a 36-kda protein, which provokes a very early immune response against leishmania infection. there are several reports on the expression of lack through different life-cycle stages of genus leishmania , but only a few of them have focused on l.tropica . methods: the present study provides details of the cloning...

background: cutaneous and visceral leishmaniases are present in fars province in the south of iran. the current study aimed to evaluate the inter- and intragenic diversities of leishmania species isolated from patients with leishmaniasis in fars province, using pcr-based analyses and dna sequencing of  the n-acetylglucosamine-1-phosphate transferase ( nagt ) gene. methods: clinical samples were...

background: cutaneous leishmaniasis constitutes a major public health problem in many parts of the world including iran. the primary objective of this study was to identify leishmania spe­cies in endemic districts of kerman province, south-eastern iran . methods: this study was conducted by random sampling as cross- sectional descriptive between 2008 and 2010. overall, 203 skin scraping smears ...

leishmaniasis is caused by parasitic protozoa of the genus leishmania. cutaneous leishmaniasis (cl) is a complex disease with wide spectrum of clinical manifestations. in order to identify leishmania species causing cl in isfahan by a definite molecular technique (pcr method), this study was undertaken over 2010- 2011. 124 patients with suspicious lesion of leishmaniasis and positive direct sme...

nocardiosis has been reported increasingly in recent two decades, probably due to improvement in isolation of the organism and increased burden of immune compromised patients. nocardia occasionally has been reported in healthy people. a case series of definitive nocardiosis (2002 to 2010), clinical characteristics, underlying diseases, immune status and in-patient outcome were studied in a tert...