OBJECTIVE To determine whether the use of age adapted D-dimer cut-off values can be translated to primary care patients who are suspected of deep vein thrombosis. DESIGN Retrospective, cross sectional diagnostic study. SETTING 110 primary care doctors affiliated with three hospitals in the Netherlands. PARTICIPANTS 1374 consecutive patients (936 (68.1%) aged >50 years) with clinically sus...

Objective To determine whether the use of age adapted D-dimer cut-off values can be translated to primary care patients who are suspected of deep vein thrombosis. Design Retrospective, cross sectional diagnostic study. Setting 110 primary care doctors affiliated with three hospitals in the Netherlands. Participants 1374 consecutive patients (936 (68.1%) aged >50 years) with clinically suspected...

Please answer “yes” or “no”: 1. Does the mass function for clusters of galaxies cut off exponentially? 2. Does the luminosity function for galaxies cut off exponentially? 3. Is the dependence of virial velocity on galaxy luminosity a power law? 4. Does the velocity function for galaxies cut off exponentially?

Since 2007, one-step nucleic acid amplification (OSNA) has been used as a diagnostic system for sentinel lymph node (SLN) examination in patients with breast cancer. This study aimed to define a new clinical cut-off of CK19 mRNA copy number based on the calculation of the risk that an axillary lymph node dissection (ALND) will be positive. We analyzed 1529 SLNs from 1140 patients with the OSNA ...

BACKGROUND D-dimer testing to rule out deep vein thrombosis is less useful in older patients because of a lower specificity. An age-adjusted D-dimer cut-off value increased the proportion of older patients (>50 years) in whom pulmonary embolism could be excluded. We retrospectively validated the efficacy of this cut-off combined with clinical probability for the exclusion of deep vein thrombosi...

BACKGROUND & OBJECTIVES Several studies have raised the suspicion that the body mass index (BMI) cut-off for overweight as defined by the WHO may not adequately reflect the actual overweight status. The present study looked at the relationship between BMI and body fat per cent (BF %) / health risks (hypertension and type 2 diabetes) in male residents of Lucknow city, north India to evaluate the...

BACKGROUND Overweight and obesity increase the risk of elevated blood pressure; most of the studies that serve as a background for the debates on the optimal obesity index cut-off values used cross-sectional samples. The aim of this study was to determine the cut-off values of anthropometric markers for detecting hypertension in Chinese adults with data from prospective cohort. METHODS This s...

BACKGROUND Age-adjusted D-dimer cut-off has recently been proposed to increase D-dimer usefulness in older patients suspected of pulmonary embolism (PE). OBJECTIVE We externally validated this age-adjusted D-dimer cut-off using different D-dimer assays in a multicenter sample of emergency department patients. METHODS Secondary analysis of three prospectively collected databases (two Europea...

in this paper, a new guidance method for surface to surface ballistic missiles without mandatory engine cut-off will be presented. the complexity of solid fuel engine cut-off demands a comprehensive method for guiding these missiles. in the method presented in this paper, a certain guidance law is applied such that by transmitting appropriate commands to the control system, by changing the miss...