Although it has been inferred that alteration of erythrocyte shape causes cell clearance. no direct measure of the effect of varying shape on clearance has been made. In this study, the protein oxidant, diamide, was employed to fix rat erythrocytes in altered shapes produced by the addition of different amphipaths or by changes in membrane structure. Clearance of cells in vivo as measured by 51...

1. Hoyt WF. Ophthalmoscopy of the retinal nerve fibre layer in neuroophthalmologic diagnosis. Aust J Ophthalmol. 1976;4(1):14-34. doi:10.1111 /j.1442-9071.1976.tb00846.x. 2. Unsöld R, Hoyt WF. Band atrophy of the optic nerve: the histology of temporal hemianopsia. Arch Ophthalmol. 1980;98(9):1637-1638. 3. Kupersmith MJ, Krohn D. Cupping of the optic disc with compressive lesions of the anterior...

A novel plasma treatment method/plasma source called cupping-assisted plasma treatment/ source for skin disinfection is introduced. The idea combines ancient Chinese ‘cupping’ technology with plasma sources to generate active plasma inside an isolated, pressurecontrolled chamber attached to the skin. Advantages of lower pressure include reducing the threshold voltage for plasma ignition and imp...

Slit-lamp examination and stereoscopic fundus photography were found to be helpful in differentiating between physiological and glaucomatous cupping of the disc. Vertical ovalness of any cup in the disc should raise the suspicion of glaucoma, and the magnitude of the vertical cup: disc ratio is of particular significance.

We propose that age-related alterations in optic nerve head (ONH) biomechanics underlie the clinical behavior and increased susceptibility of the aged ONH to glaucomatous damage. The literature which suggests that the aged ONH is more susceptible to glaucomatous damage at all levels of intraocular pressure is reviewed. The relevant biomechanics of the aged ONH are discussed and a biomechanical ...

We evaluated the ability of spectral-domain optic coherence tomography (SD-OCT) to differentiate large physiological optic disc cupping (LPC) from glaucomatous cupping in eyes with intraocular pressure (IOP) within the normal range. We prospectively enrolled patients with glaucoma or presumed LPC. Participants had optic discs with confirmed or suspected glaucomatous damage (defined as a vertica...

AIMS To evaluate the effect of acute elevation of intraocular pressure (IOP) on optic disc cupping. METHODS 10 emmetropic and 10 myopic volunteers were included in this study. The cup area (CA) and cup volume (CV) of the optic disc were determined with the Heidelberg retina tomograph (HRT). After baseline determinations, a suction cup was used to increase the intraocular pressure (IOP) to 20-...