OBJECTIVES While computed tomography colonography (CTC) has become a non-invasive alternative to traditional colonoscopy, superficial lesions tend be harder detect, with reports of <2 mm in height being missed. Therefore, for the evaluation lesion detectability using CTC, optimizing scan parameters becomes important. In this study, we investigate effect reconstructed matrix size from CTC on con...

Blood tests to detect circulating tumor cells (CTC) offer great potential to monitor disease status, gauge prognosis, and guide treatment decisions for patients with cancer. For patients with brain tumors, such as aggressive glioblastoma multiforme, CTC assays are needed that do not rely on expression of cancer cell surface biomarkers like epithelial cell adhesion molecules that brain tumors te...

To the Editor: The presence of circulating tumor cells (CTC) in the peripheral blood of cancer patients has attracted a great deal of attention among investigators. The clinical significance of CTC has probably best been established in breast cancer, where it has been shown that the detection of CTC in metastatic patients correlates with early clinical relapse and patient death [1]. Gene expres...

In recent years, Long Short-Term Memory Recurrent Neural Networks (LSTM-RNNs) trained with the Connectionist Temporal Classification (CTC) objective won many international handwriting recognition evaluations. The CTC algorithm is based on a forward-backward procedure, avoiding the need of a segmentation of the input before training. The network outputs are characters labels, and a special non-c...

BACKGROUND Computed tomographic colonography (CTC) is a new technique for detecting colonic neoplasms. Data on the utility of this method in the Indian population are limited. METHODS Forty-two patients with symptoms of colonic disease underwent CTC and conventional colonoscopy (CC) within one week of each other and the findings at these two investigations were compared. RESULTS The entire ...

BACKGROUND Quantification of circulating tumor cells (CTC) is valuable for evaluation of non-small cell lung cancer (NSCLC). The sensitivity of current methods constrains their use to detect rare CTCs in early stage. Here we evaluate a novel method, ligand-targeted polymerase chain reaction (LT-PCR), that can detect rare CTCs in NSCLC patients. METHODS CTCs were enriched by immunomagnetic dep...

BACKGROUND Presence of circulating tumor cells (CTC) in patients with metastatic breast, colorectal and prostate cancer is indicative for poor prognosis. An automated CTC (aCTC) algorithm developed previously to eliminate the variability in manual counting of CTC (mCTC) was used to extract morphological features. Here we validated the aCTC algorithm on CTC images from prostate, breast and color...

BACKGROUND Community-based therapeutic care (CTC) is a new strategy in the arsenal of techniques to manage complex nutritional emergencies in rural communities. The CTC approach uses a newly developed ready-to-use therapeutic food, Plumpynut, to rehabilitate severely malnourished children in their home communities. Emerging literature has suggested the CTC strategy yielded results that were sup...

PURPOSE The development of tumor-specific markers to select targeted therapies and to assess clinical outcome remains a significant area of unmet need. We evaluated the association of baseline circulating tumor cell (CTC) number with clinical characteristics and survival in patients with castrate metastatic disease considered for different hormonal and cytotoxic therapies. EXPERIMENTAL DESIGN...

PURPOSE Communities That Care (CTC) is a prevention system designed to reduce levels of adolescent delinquency and substance use through the selection and use of effective preventive interventions tailored to a community's specific profile of risk and protection. This article describes early findings from the first group-randomized trial of CTC. METHODS A panel of 4407 fifth-grade students wa...