Long term pulmonary exposure to crystalline silica leads to silicosis that manifests progressive interstitial fibrosis, eventually leading to respiratory failure and death. Despite efforts to eliminate silicosis, clinical cases continue to occur in both developing and developed countries. The exact mechanisms of crystalline silica-induced pulmonary fibrosis remain elusive. Herein, we find that ...

Liquid-crystalline nanoparticles represent an exciting class of new materials for a variety of potential applications. By combining supramolecular ordering with the fluid properties of the liquid-crystalline state, these materials offer the possibility to organise nanoparticles into addressable 2-D and 3-D arrangements exhibiting high processability and self-healing properties. Herein, we revie...

A case of infectious crystalline keratopathy that affects mainly the posterior stroma is presented. Crystalline infiltrates presented after multiple epithelial defects and chronic topical steroid use following a penetrating keratoplasty in this patient. His epithelial defects persisted and given the deep location of the crystalline infiltrates, a penetrating keratoplasty was performed again. Sl...

Crystalline membranes are two-dimensional membranes whose constituent particles form a crystalline mesh. A good example is free standing graphene where carbon atoms form a membrane with a hexagonal lattice structure. What distinguishes crystalline membranes from conventional two-dimensional crystals is the embedding in a three dimensional space which allows for fluctuations not only within the ...

The reflection-absorption infrared (RAIRS) spectra of 1-ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide ([EMIM]Tf(2)N) are presented for liquid as well as for amorphous and crystalline solid films. The liquid and amorphous films show rather similar spectra, indicating that the film structure is similar in both cases. On the other hand, these spectra differ considerably from those of...

Crystalline nephropathy is a rare yet well-known condition associated with multiple myeloma and other light chain-secreting disorders. Paraproteins that are resistant to proteolysis crystallize within proximal tubular cells and cause light-chain proximal tubulopathy, which presents clinically as Fanconi syndrome. Podocytes are rarely affected, and the crystalline inclusions within podocytes are...

In the course of preparing carbamyl phosphate synthetase from frog liver, a crystalline protein fraction was obtained which proved to be glutamate dehydrogenase. Because of the considerable interest in this enzyme and the striking differences in certain properties of this enzyme from different animal sources (l-6), it seemed of importance to study the kinetic properties of crystalline frog live...

The isolation of two proteinases in crystalline form from extracts of beef pancreas has been described by Kunitz and Northrop (1). These enzymes have been named trypsin and chymotrypsin. Previous publications (2) from this laboratory have reported the finding of a series of synthetic peptide derivatives which were readily hydrolyzed by crystalline chymotrypsin. In this communication a synthetic...