Information on thermal history of skin tissue and iceball formation is critical for successful cutaneous cryosurgery. This paper presents a numerical analysis of tissue freezing during skin cancer treatment with liquid nitrogen (LN2). A simplified mathematical model is constructed by including the bio-physical processes of the freezing tissues and quantifying LN2 spray cooling with a convective...

In a study of the time course and nature of the sensory loss after cryosurgery the forearms of nine normal subjects were treated with liquid nitrogen using freeze times currently employed in clinical practice in Britain. Ability to appreciate touch, pinprick, and cold in the treated areas was tested at regular intervals and biopsy samples taken to investigate the pathogenesis. Appreciation of a...

This article reviews the current status of the prostatic cryosurgery in the management of patients with prostate cancer. Recent advances in cryoablative technology have allowed to treat these patients successfully with decreased morbidity. Using transrectal high-resolution ultrasound imaging, prostate cryotherapy is delivered with multiple ultrathin (17-gauge) cryo-needles, via percutaneous tra...

BACKGROUND Treatments for cervical lesions through the years have been varied, from cauterization with chemicals, to the use of electrosurgery with diathermic loop, however the method to be chosen should be one that offers greater benefits and lower risks. OBJECTIVE Present a well structured study protocol in patients presenting with cervical disease and offer treatment cryotherapy as ablativ...