Abstract Background Inflammatory bowel disease (IBD) commonly affects women and men during the reproductive years.The effect of burden on fertility in these patients is a common concern for them. ECCO guidelines establish that active associated with decreased but studies regarding this topic are low quality outdated. Aims to investigate CD fertility, studying ovarian reserve as well global Sert...

OBJECTIVE The purpose of this article is to review the technique of performing MR enterography examinations and to review the imaging findings suggestive of Crohn disease. This article will also allow the reader to self-assess and improve his or her skills in the performance and interpretation of MR enterography examinations. CONCLUSION MRI plays a valuable role in providing accurate informat...

AIM To define sensitive and reliable Doppler parameters for measurements in the superior mesenteric artery and mural arteries of affected bowel loops used in the assessment of Crohn disease activity. METHODS We performed cross-sectional study at a tertiary care setting in Zagreb, Croatia, between January 2001 and March 2005. We measured arterial flow in the superior mesenteric artery and affe...

A small number of cases of Crohn disease associated with myelodysplastic syndromes or leukemia have been reported in adults in the last 25 years in the English-language medical literature. The authors report a case of a 9-year-old boy who developed Crohn disease and myelodysplastic syndrome concurrently. Analysis of his bone marrow showed a chromosome 20 abnormality. Although chromosome 20 abno...

Infliximab is one of the most widely used tumour necrosis factor-alpha (TNF) inhibitors for control of Crohn disease. We report the case of a patient with ileocolonic Crohn disease developing major arterial thrombosis after treatment with infliximab. After conservative management and infliximab withdrawal, thrombus dissolution and vessel recannalisation were observed. Few cases of arterial thro...

Crohn's disease may affect any segment of the gastrointestinal tract; however, isolated duodenal involvement is rather rare. It still remains a complex clinical entity with a controversial management of the disease. Initially, patients with duodenal Crohn' s disease (DCD) are managed with a combination of antiacid and immunosuppressive therapy. However, medical treatment fails in the majority o...

This Is a Story about Controls Unraveling the pathogenesis of a complex disease is daunting. Variation in multiple genes and multiple environmental factors could be at play, as could variation in the interactions of these risk factors with each other. Lest you despair, Cadwell et al. prove that it is possible to reveal features of the disease process through a careful set of experiments with go...