The occurrence of a noninfectious interstitial lung disease is a rare but life-threatening side effect of infliximab, an antitumor necrosis factor alpha antibody. The following case report of a patient with Crohn disease shows an extremely dramatic progression to a severe acute respiratory distress syndrome.

CSH is a very uncommon lesion and is distinctly unusual in the brain. We report a case of CSH within the brain parenchyma in a 27-year-old woman with Crohn disease. Advanced radiologic imaging and anatomic pathology correlation allow this report to serve as a reference for future similar cases.

Nine individuals with ulcerative colitis or Crohn disease grew up or lived in Plains, Montana, a 1,200-person community adjacent to the Clark Fork River near herds of free ranging Rocky Mountain bighorn sheep. This inflammatory bowel disease outbreak is similar to others that have occurred along rivers contaminated by animal feces.

We present the case of recurrent fractures and hypophosphataemic rickets that occurred in a young man who received parenteral ferrous carboxymaltose (FCM) for chronic iron deficiency associated with Crohn disease. The effect of FCM on bone and mineral metabolism and the frequency of this disorder are discussed.

An increasing array of treatments such as immunosuppressive drugs and tumor necrosis factor inhibitors can offer patients with ulcerative colitis and Crohn disease improved relief from symptoms with fewer adverse effects. Several additional drugs have shown promise, including nicotine, antimicrobials, and heparin.

Conflicting data exist regarding the association between pre-operative monoclonal anti-tumor necrosis factor-alpha antibody therapy with infliximab for Crohn disease and chronic ulcerative colitis, and the occurrence of post-operative complications. This report reviews the current literature that supports and refutes this association.

A 52-year-old man originally diagnosed with ulcerative colitis presented with an inflamed small-bowel stricture in the ascending limb of an ileoanal J-pouch and was subsequently diagnosed with Crohn disease. The stricture did not respond to medical treatment with either methotrexate or adalimumab, and repeated endoscopic balloon dilation relieved the patient’s obstructive symptomsonly briefly. ...

BACKGROUND The reported prevalence of gallstone disease (GD), defined as current gallstones or previous cholecystectomy for gallstones, in patients with Crohn disease ranges from 13% to 34%. The aim of this study was to characterize the still undefined risk factors of this complication. METHODS A total of 330 consecutive patients with Crohn disease (189 males and 141 females aged 17-82 years,...

Extraintestinal manifestations (EIMs) cause increased morbidity and decreased quality of life in Crohn disease (CD). Ankylosing spondylitis (AS) belongs to EIMs. Very little is known on the clinical features of CD concomitant with AS. This study is to investigate the clinical features of CD patients with AS.We retrospectively collected all CD patients with AS in our hospital, and established a ...

lapping clinical, endoscopic and histological features. Differential diagnosis may become extremely difficult in the setting of Salmonella infections, complicating undiagnosed IBD. We report the case of an elderly patient admitted to hospital due to acute enteritis secondary to Salmonella infection, complicating undiagnosed Crohn’s disease (CD) and we highlight the diagnostic and therapeutic di...