augmentation of the maxillary sinus is a highly predictable and effective procedure to increase bone volume in the posterior maxilla. Success rates are equal to or better than that of all implants placed in nongrafted maxillary bone in or out of the sinus. Consequently, even in situations where the interocclusal dimension is normal or only moderately increased due to loss of bone height, bone a...

OBJECTIVE To evaluate marginal bone loss over 3 years around immediate microthreaded implants placed in the maxillary anterior/esthetic zone and immediately restored with single crowns. MATERIAL AND METHODS Seventy-one implants (with microthreads up to the platform--rough surface body and neck, internal connection and platform switching) were placed in fresh extraction sockets in the maxillar...

BACKGROUND The osteoconductive properties of collagen containing xenogeneic bone blocks (CCXBB) remain unclear. The aim of this prospective single-arm clinical study was to assess the histological outcomes of CCXBB blocks used as bone replacement grafts for lateral bone augmentation procedures. METHODS In 15 patients with severe horizontal alveolar ridge resorption, lateral augmentation proce...

Osteopontin (OPN) was expressed in murine wild-type osteoclasts, localized to the basolateral, clear zone, and ruffled border membranes, and deposited in the resorption pits during bone resorption. The lack of OPN secretion into the resorption bay of avian osteoclasts may be a component of their functional resorption deficiency in vitro. Osteoclasts deficient in OPN were hypomotile and exhibite...

This study aimed to investigate the influence of implant design (in terms of diameter, length, and thread shape), in-bone positioning depth, and bone posthealing crestal morphology on load transfer mechanisms of osseointegrated dental implants based on platform-switching concept. In order to perform an effective multiparametric comparative analysis, 11 implants different in dimensions and in th...

conclusions alendronate may be considered a therapeutic option for improving the bone formation process and reducing resorption in different bone grafting procedures. further detailed studies should focus on dosage and time-dependent effects of alendronate on bone remodeling. results at 6 weeks, the bone area was significantly larger in the xenograft-alendronate group (33.0% ± 5.0%) than in the...

Nobiletin, a polymethoxy flavonoid (PMF), inhibits systemic bone resorption and maintains bone mass in estrogen-deficient ovariectomized mice. This study examined the anti-inflammatory effects of PMFs, nobiletin, and tangeretin on lipopolysaccharide (LPS)-induced bone resorption. Nobiletin and tangeretin suppressed LPS-induced osteoclast formation and bone resorption and suppressed the receptor...

BACKGROUND AND AIMS Complete and predictable regeneration of tissue lost as a result of infection or trauma is the ultimate goal of periodontal therapy. Various graft materials have been successfully used in the treatment of intrabony defects. The purpose of this study was to evaluate the use of a decalcified freeze-dried bone allograft (Cerabone) with the autogenous bone graft as a gold standa...

OBJECTIVE In the last decade, several investigators have reported that standard length implants (SLIs) have achieved excellent results but no report regarding SLIs (i.e. SLI, length=13 mm) inserted into alveolar bone sites previously augmented with frozen bone (FB) is available. The aim of this study was to evaluate the clinical outcome of SLIs inserted into alveolar bone sites previously augme...