OBJECTIVE To see whether the distribution patterns of phosphorylated 43kDa TAR DNA-binding protein (pTDP-43) intraneuronal inclusions in amyotrophic lateral sclerosis (ALS) permit recognition of neuropathological stages. METHODS pTDP-43 immunohistochemistry was performed on 70 μm sections from ALS autopsy cases (N = 76) classified by clinical phenotype and genetic background. RESULTS ALS ca...

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cranial injury, as it is known today, is not a new concern of modern medicine. on stepping on the earth, the man was in reality encountered with various types of injuries, particularly those of a cranial nature. leading a life, whether wild or civilized, has always been associated with injuries for human race from the very beginning of birth. therefore, managing cases of this type has gradually...

Objective
 Headache is a common complaint in childhood.
 While the etiology usually benign, such as migraine
 or tension-type headache, cranial imaging often
 performed on patients to identify any missed serious
 underlying pathology. In present study we assess
 and clinical characteristics of headaches
 children establish diagnostic contribution of
 meth...

traumatic brain injury is a leading cause of disability and death from injury in the world. the interleukin-1 (il-1) is a family of cytokines that act as key mediators of the inflammatory response peripherally and centrally. based on many studies, researchers found that the il-1 is the well-known molecule in relation to acute tbi in the models of both focal and diffuse injuries. the il-1 family...

conclusions along with the technological advancement, different materials are employed according to the size of the cranium defect and the age of the case. the application of split costa cranioplasty for the small cranium defects in the region of patient’s face is the method with the least possibility of complications, and its cosmetic and functional results are quite promising. introduction os...

This article presents cases of treponematosis in at least five individuals from different archeological sites southern North Eastern Argentina and discusses how these were linked to the ways life pre-Hispanic groups that inhabited this region for 2000 years. We carried out reanalysis reinterpretation some pathological cases, including a comparison between our observations previous diagnoses mad...

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Objective: The cranial base harbours numerous foramina, and the anatomical properties of foramina are crucial in clinical interventions. purpose current study is to evaluate possible asymmetries regarding middle posterior fossae using 3D reconstructions high-resolution computed tomography (CT) images. Patients Methods: High-resolution CT images 253 female 287 male adult patients were used study...