Extra medullary plasmacytomas occurring as solitary (primary) tumours or secondary manifestations of multiple myeloma most often involve the upper airways and paranasal sinuses. The skull is one of the rarest sites of extra medullary plasmacytoma. Myelomatous deposits in dural reflections distant from the bony skull, i.e. tentorium and falx, are rarer, and probably result from dissection along ...

BACKGROUND Radiation therapy is often used in the treatment of pituitary tumor. Diplopia due to radiation damage to the ocular motor cranial nerves has been infrequently reported as a complication in this clinical setting. METHODS Retrospective case series of 6 patients (3 men and 3 women) with pituitary adenoma, all of whom developed diplopia following transsphenoidal resection of pituitary ...

Peripheral facial palsy is a clinical entity, which may be presented as the first symptom of multiple sclerosis (MS). Although MS is mostly a multifocal chronic inflammation of the central nervous system, peripheral nervous system can also be involved. Isolated cranial nerve palsies are rare and occur in 1.6% of MS patients. In this report, a case is presented of a 35-year-old woman who develop...

A 69-year-old man presented with a recent history of painless diplopia and left eye conjunctival injection. He had a cutaneous adenosquamous carcinoma removed from the left forehead 3 years before. The examination showed complete left ophthalmoplegia, exophthalmos, ptosis, and ipsilateral V1 hypoesthesia. Brain MRI revealed thickening and contrast enhancement of the external wall of the left ca...

Sixty-three patients with third cranial nerve palsies (CNPs), either isolated (31) or in association with other neurologic deficits (32), underwent neuroophthalmologic and neuroradiologic evaluation. Discrepancies between the clinical and radiologic evaluations were analyzed and useful clinical presenting symptoms were identified. Microvascular infarction secondary to diabetes mellitus and/or h...

We report here the history of a 52-year old woman with diabetes mellitus for 10 years and secondary hypothyroidism (low TSH) who presented with chronic persistent headache for 6 years and sudden onset of complete blindness of 24 hours duration, admitted to our unit at National Hospital of Sri Lanka in July 2004 . On the first admission in 1998, a cranial CT scan demonstrated a lesion suggestive...

Case presentation We report the case of localised granulomatosis with polyangitis in a 27 year old Caucasian gentleman who presented with multiple cranial neuropathies. He reported diplopia, hearing loss, dysphagia and dysarthria due to involvement of VI, XIII, IX, X and XII cranial nerves. A cerebral MRI demonstrated pachymeningitis along with mastoid changes and additional diagnostic workup s...