Background: Most of the medical colleges in India follow the Conventional Practical Examination (CPE) system for evaluation of practical or clinical skills. This method has several flaws such as inter-examiner marks variation, favouritism, varying difficulty level of different experiments etc. which prevents uniform marking. Objective Structured Practical Examination (OSPE), conceptualised by H...

Cpe mice have a point mutation in carboxypeptidase E (Cpe), an exopeptidase that removes C-terminal basic amino acids from intermediates to produce bioactive peptides. The mutation renders the enzyme inactive and unstable. The absence of Cpe activity in these mutants leads to abnormal processing of many peptides, with elevated levels of intermediates and greatly reduced levels of the mature pep...

Early development in Xenopus laevis is programmed in part by maternally inherited mRNAs that are synthesized and stored in the growing oocyte. During oocyte maturation, several of these messages are translationally activated by poly(A) elongation, which in turn is regulated by two cis elements in the 3' untranslated region, the hexanucleotide AAUAAA and a cytoplasmic polyadenylation element (CP...

Brain metastasis is the most commonly occurring intracranial tumor whose incidence seems to be increasing. With standard therapy, the average survival time of patients is approximately 8 months, and treatment often leads to neurologic dysfunction in long-term survivors, emphasizing the need for novel therapeutics. Clostridium perfringens enterotoxin (CPE) has recently been shown to rapidly and ...

Cloud point extraction (CPE) is a well-established technique for the preconcentration of hydrophobic species from water without the use of organic solvents. Subsequent analysis is then typically performed via atomic absorption spectroscopy (AAS), UV-vis spectroscopy, or high performance liquid chromatography (HPLC). However, the suitability of CPE for electroanalytical methods such as stripping...

The prevalence of carbapenemase-producing Enterobacteriaceae (CPE) in our hospital increased beginning in 2009. We aimed to study the clinical and molecular epidemiology of these emerging isolates. We performed a retrospective review of all adult patients with clinical cultures confirmed as CPE by positive modified Hodge test from 5/2009- 5/2010 at the University of Michigan Health System (UMHS...

Enterotoxin-producing Clostridium perfringens type A isolates are an important cause of food poisoning and non-food-borne human gastrointestinal diseases, e.g., sporadic diarrhea (SPOR) and antibiotic-associated diarrhea (AAD). The enterotoxin gene (cpe) is usually chromosomal in food poisoning isolates but plasmid-borne in AAD/SPOR isolates. Previous studies determined that type A SPOR isolate...

This study was conducted on 52 final year BDS students of Lahore Medical and Dental College, Lahore to compare their performance in Objectively structured practical examinations (OSPE) and Conventional Orthodontic practical examination (CPE).A mock examination, comprising of CPE and OSPE was conducted in the Orthodontic department for summative assessment before the final professional universit...

Clinical Pastoral Education (CPE) is experiential learning of the art and science of pastoral care. CPE students increase capacities in psychological strengths such as self-awareness and empathy, and improve skills in interpersonal and inter-professional relationships. Previous research has documented different kinds of change and experiences for students depending on the length of the CPE unit...

In this study, the trace amounts of erythrosine, as a food dye is determined by cloud point extraction-scanometry (CPE-Scanometry) as a new, facile, available, fast, sensitive, and low cost method. The method is based on the CPE of analyte from aqueous solution, diluting the extracted surfactant-rich phase with ethanol, transfer to Plexiglascell and scanning the cells containing the analyte sol...