BACKGROUND Several frameworks have been constructed to analyse the factors which influence and shape the uptake of evidence into policy processes in resource poor settings, yet empirical analyses of health policy making in these settings are relatively rare. National policy making for cotrimoxazole (trimethoprim-sulfamethoxazole) preventive therapy in developing countries offers a pertinent cas...

Bacterial infections may cause disease and death. Infants and children are often subject to bacterial infections. Antimicrobials kill bacteria protecting the infected patients andreducing the risk of morbidity and mortality caused by bacteria. The antibiotics may lose their antibacterial activity when they become resistant to a bacteria. The resistance to different antibiotics in a bacteria is ...

A study of antimicrobial agents sensitivity using the microdilution system incorporated to identification/susceptibility of non-fermenting gram-negative of Microscan panels, was made, taking into account the breakpoints in the Clinical and Laboratory Standards Institute (CLSI). Studied strain was sensitive to most of the antibiotics tested as: cefotaxime, cefepime and piperacillin/tazobactam, g...

A male infant of 32 weeks' gestational age who presented with recurrent apnoea on the second day of life was shown to have an Escherichia coli K1 antigen meningitis. Relapse occurred 6 days after an adequate systemic course of gentamicin and chloramphenicol and intrathecal gentamicin. This was successfully treated with intraventricular gentamicin and systemic cotrimoxazole. The need to maintain...

The authors describe a case of severe debilitating diarrhea due to isosporiasis in a two year old child, a known case of systemic vasculitis receiving prolonged corticosteroids therapy, an association rarely reported previously. It was refractory to treatment with dihydrofolate reductase inhibitor combined with sulfonamide such as cotrimoxazole to which isosporiasis usually responds well and is...

9. Arem R, Garber AJ, Field JB. Sulfonamide-induced hypoglycemia in chronic renal failure. Arch Intern Med. 1983;143:827--9. 10. Hughes CA, Chik CL, Taylor GD. Cotrimoxazole-induced hypoglycemia in an HIV-infected patient. Can J Infect Dis. 2001;12:314--6. 11. Shattner A, Rimon E, Green L, Coslovsky R, Bentwich Z. Hypoglycaemia induced by co-trimoxazole in AIDS. BMJ. 1988;297: 740. Juan Caro , ...

Since 1990s Salmonella typhi has developed resistance simultaneously to all the drugs used in first line treatment (chloramphenicol, cotrimoxazole and ampicillin) and are known as Multi Drug Resistant typhoid fever (MDRTF). There are some reports of reemergence of fully susceptible strain to first line drugs(2). But these reports are few and unless antibiotic sensitivity testing shows the organ...