BACKGROUND Compliant flooring, broadly defined as flooring systems or floor coverings with some level of shock absorbency, may reduce the incidence and severity of fall-related injuries in older adults; however, a lack of synthesized evidence may be limiting widespread uptake. METHODS Informed by the Arksey and O'Malley framework and guided by a Research Advisory Panel of knowledge users, we ...

Civil remedies allow an individual to coerce a third party into taking action against offenders who are imposing hardship on the individual initiating the remedy. Thus, there is a disjunction between the individual who initiates and benefits from a civil remedy and the entity that bears most of the cost of implementing the remedy. At their best, civil remedies can make negligent organizations r...

BACKGROUND Whilst it is recommended that babies are breastfed exclusively for the first six months, many mothers do not maintain breastfeeding for this length of time. Previous research confirms that women and midwives value financial incentives for breastfeeding, but limited research has explored the wider acceptability of these interventions to the general public. This paper examines opinion ...

BACKGROUND Reablement is a time-limited intervention that aims to support people to regain independence and enable them to resume their daily activities after they return home from an in-patient care setting, or to maintain independence to enable them to remain at home. There is some evidence that reablement can enhance independence and has the potential to contain costs. However, reablement se...

www.pacb.com/denovo In the days of Sanger sequencing, organisms considered most scientifically important were targeted for high-quality, finished genomes. There was no question that this was an expensive and laborious goal, but it was widely accepted that a finished genome answered questions that no draft assembly ever could. As short-read sequencing technologies became available, they were emb...

OBJECTIVE We estimated the investment needs, population health gains, and cost-effectiveness of different policy options for scaling-up prevention and treatment of HIV in the 10 countries that currently comprise 80% of all people living with HIV in sub-Saharan Africa (Ethiopia, Kenya, Malawi, Mozambique, Nigeria, South Africa, Tanzania, Uganda, Zambia, and Zimbabwe). DESIGN We adapted the est...

BACKGROUND This paper is part of a project to identify the proportion of the burden of each mental disorder averted by current and optimal interventions, and the cost-effectiveness of both. AIMS To use epidemiological data on schizophrenia to model the cost-effectiveness of current and optimal treatment. METHOD Calculate the burden of schizophrenia in the years lived with disability (YLD) c...