Although each subdivision of primary somatosensory cortex (SI) receives dense input from the thalamus, but the exact location and type of information that the fibers convey have not been identified yet. In the present study, the exact source of thalamocortical fibers to areas 2 and 3b was investigated using tract-tracing techniques. Following injection of tracer into area 3b, labeled neurons ...

Background & Aims: Diabetes mellitus influences the reproductive system. Since investigations have showed that cinnamon may have an improving effect on diabetes, this study was designed to investigate the effect of cinnamon extract on the ovary structure in diabetic rats. Methods: A total of 24 female wistar rats (186±15gr) were randomly divided into 4 equal groups of control, control + cinnamo...

Neuroinflammation seems to be involved in the pathophysiology of Huntington’s Disease (HD), but its specific role on different stages disease, especially later stages, remains understood. Here in, we investigated concentrations cytokines, chemokines and neurotrophic factors striatum frontal cortex 24-month-old BACHD mice, a murine model that displays several behavioral pathological features hum...

The properties of microglia largely differ depending on aging as well brain regions. However, there are few studies that investigated the functional importance such heterogeneous at molecular level. Voltage-gated proton channel, Hv1/VSOP, could be one candidates which confers heterogeneity among since it regulates oxidative stress in age-dependent manner. In this study, we found Hv1/VSOP shows ...

Cognitive planning, the ability to develop a sequenced plan achieve goal, plays crucial role in human goal-directed behavior. However, specific of frontal structures planning is unclear. We used novel and ecological task, that allowed us separate period from execution period. The spatio-temporal dynamics EEG recordings showed induced progressive sustained increase frontal-midline theta activity...

Episodic memory retention and retrieval decline are the most common impairments observed in amnestic mild cognitive impairment (aMCI) patients who progress to Alzheimer's disease (AD). Clinical electroencephalography research shows that with dementia due AD exhibit a slowing of neural electrical activity parietal cortex. Memory has further suggested successful performance is associated changes ...

Brillouin microscopy is a new form of optical elastography and an emerging technique in mechanobiology biomedical physics. It was applied here to map the viscoelastic properties human hair determine effect bleaching on properties. For samples, longitudinal measurements (i.e. along fibre axis) revealed peaks at 18.7 20.7 GHz location cuticle cortex, respectively. treated with agent, frequency sh...