purpose: to evaluate the correlation between corneal power and corneal horizontal white to white diameter in myopic patients scheduled for lasik surgery. methods: overall, in 840 eyes of 420 myopic subjects scheduled for lasik, horizontal white to white diameter and mean corneal power were obtained using orbscan ii. pearson correlation test and regression analysis were used to detect any correl...

purpose : to evaluate the effects of topical sesame oil in the treatment of severe corneal alkali injury in rabbits methods : in a double-blind experiment, 30 healthy white rabbits were randomized into a sesame oil treatment group (n=15) and a control group (n=15). under general anesthesia, severe corneal alkali injuries were induced by application of 1 n sodium hydroxide for 40 seconds to the ...

purpose: to present two patients with acute corneal hydrops, superimposed with infectious keratitis using topical steroids. patients and findings: the first case was a 44-year-old man with acute corneal hydrops in his left eye which was on topical steroids for one week. visual acuity was hand motion at presentation and there was a large epithelial defect with stromal infiltration and corneal ed...

Human corneal fibroblasts (HCF) and corneal stromal stem cells (CSSC) each secrete and organize a thick stroma-like extracellular matrix in response to different substrata, but neither cell type organizes matrix on tissue-culture polystyrene. This study compared cell differentiation and extracellular matrix secreted by these two cell types when they were cultured on identical substrata, polycar...

PURPOSE To characterize human limbal epithelial cells based on the expression levels of nuclear protein p63 and the nucleus-to-cytoplasm (N/C) ratio. METHODS Limbal, peripheral, and central corneal epithelia were separated from the stroma by Dispase II and subsequently were treated with trypsin to obtain single-cell suspensions. Cytospin smears of the cell suspensions were double immunostaine...

Limbal epithelial stem cells (LESC) residing at the corneal periphery are largely responsible for maintaining corneal optical transparency by continuously supplying new corneal epithelial cells, which mature during their radial migration to the central cornea. Diabetes mellitus (DM) affects all the structures of the eye including the cornea. Frequent epithelial erosions, delayed wound healing, ...

PURPOSE The studies reported here were performed to analyze the roles of Sproutys (Sprys), downstream targets and negative feedback regulators of the fibroblast growth factor (FGF) signaling pathway, in lens and corneal differentiation. METHODS Spry1 and -2 were conditionally deleted in the lens and corneal epithelial precursors using the Le-Cre transgene and floxed alleles of Spry1 and -2. A...

Background: To investigate the relationship between high-order aberration (HOA) changes and RCST/CT (residual corneal stroma thickness/corneal thickness) after femtosecond LASIK surgery.