PURPOSE To determine changes in higher-order aberrations (HOAs) after corneal collagen crosslinking (CXL). SETTING Cornea and refractive surgery practice. DESIGN Prospective randomized controlled clinical trial. METHODS Corneal and ocular HOAs were measured and analyzed using the Pentacam device and Ladarwave aberrometer, respectively, at baseline and 12 months after CXL. RESULTS Ninety...

The cornea is one of the principal refractive elements in the human eye and plays a crucial role in the process of vision. Keratoconus is the most common corneal dystrophy, found mostly among young adults. It is characterized by a reduced number of collagen cross-links in the corneal stroma, resulting in reduced biomechanical stability and an abnormal shape of the cornea. These changes lead to ...

Purpose: To search evidence and determine whether PRK (Photo Refractive Keratectomy) or LASIK (Laser in Situ Keratomileusis) produce a better outcome of laser vision correction for patients with atypical topography of cornea. Setting: Electronic search of laser vision correction related studies on Cochrane Library, Medline and PubMed. Method: The search was conducted over Cochrane Library, Emba...

PURPOSE A preliminary study to evaluate the outcomes of high-resolution wavefront-guided (HRWG) photorefractive keratectomy (PRK) with simultaneous corneal cross-linking (CXL) in ectasia eyes. METHODS Sixteen eyes of 11 patients (mean age 31.9±9.8 years; range: 15-48 years) with keratoconus or post-laser-assisted in situ keratomileusis ectasia underwent HRWG PRK with simultaneous CXL. Manifes...

PURPOSE The objective of this study is to describe the authors' results with intrastromal corneal ring segments (Intacs) and a new variation of lamellar keratoplasty, termed intralamellar keratoplasty (ILK), for the treatment of keratoconus (KCN) and post-laser-assisted in situ keratomileusis (LASIK) ectasia. METHODS A retrospective review of contact lens-intolerant KCN and post-LASIK ectasia...

Corneal collagen cross-linking has become the preferred modality of treatment for corneal ectasia since its inception in late 1990s. Numerous studies have demonstrated the safety and efficacy of the conventional protocol. Our understanding of the cross-linking process is ever evolving, with its wide implications in the form of accelerated and pulsed protocols. Newer advancements in technology i...

PURPOSE To compare long-term keratometric changes after penetrating keratoplasty (PK) for keratoconus and Fuchs endothelial dystrophy. METHODS We retrospectively analyzed 168 corneas after PK for keratoconus (85 eyes of 63 subjects) and Fuchs dystrophy (83 eyes of 60 subjects). Patients were examined after final suture removal at 12 months after PK to 30 years after surgery. Operations were p...

To the Editor: We read with interest the report from Drs. Abdulmassih-Gonçalves and Gonçalves.1 The authors should be commended for publishing a case of ectasia after LASIK, which was detected and addressed by collagen cross-linking. We also appreciate their willingness in sharing the preoperative raw data from rotatingScheimpflug tomography, which generated interesting information that we addr...